DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues
Homeodomains (HDs) are the second largest class of DNA binding domains (DBDs) among
eukaryotic sequence-specific transcription factors (TFs) and are the TF structural class with …
eukaryotic sequence-specific transcription factors (TFs) and are the TF structural class with …
Role of Shape Deformation of DNA-Binding Sites in Regulating the Efficiency and Specificity in Their Recognition by DNA-Binding Proteins
Accurate transcription of genetic information is crucial, involving precise recognition of the
binding motifs by DNA-binding proteins. While some proteins rely on short-range …
binding motifs by DNA-binding proteins. While some proteins rely on short-range …
[HTML][HTML] Role of Shape Deformation of DNA-Binding Sites in Regulating the Efficiency and Specificity in Their Recognition by DNA-Binding Proteins
SK Mishra, A Bhattacherjee - JACS Au, 2024 - ncbi.nlm.nih.gov
Accurate transcription of genetic information is crucial, involving precise recognition of the
binding motifs by DNA-binding proteins. While some proteins rely on short-range …
binding motifs by DNA-binding proteins. While some proteins rely on short-range …
Genome-Wide Screens Identify Genes Responsible for Intrinsic Boric Acid Resistance in Escherichia coli
B Çöl, MS Kürkçü, E Di̇bek - Biological Trace Element Research, 2024 - Springer
Boric acid (BA) has antimicrobial properties and is used to combat bacterial infections,
including Enterobacteria. However, the molecular mechanisms and cellular responses to BA …
including Enterobacteria. However, the molecular mechanisms and cellular responses to BA …
Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors
TN Vernon, JR Terrell, AV Albrecht, MW Germann… - Structure, 2024 - cell.com
Nucleobases such as inosine have been extensively utilized to map direct contacts by
proteins in the DNA groove. Their deployment as targeted probes of dynamics and …
proteins in the DNA groove. Their deployment as targeted probes of dynamics and …
Symmetry of a partially-ligated state maintained by dynamics in a negatively cooperative system
R Strawn, PS Murthy, RH Ettrich, I Pelczer… - Frontiers in …, 2024 - frontiersin.org
Symmetry was a key concept underlying the MWC model for allostery advanced in 1965 by
Monod, Wyman, and Changeux. The reciprocal interactions of symmetrically-arranged …
Monod, Wyman, and Changeux. The reciprocal interactions of symmetrically-arranged …