Perspective to precision medicine in scleroderma
K Komura, K Yanaba, JD Bouaziz, A Yoshizaki… - Frontiers in …, 2024 - frontiersin.org
Systemic sclerosis (SSc) is a rare and heterogeneous disease with no relevant
environmental trigger or significant responsible gene. It has been and will continue to be …
environmental trigger or significant responsible gene. It has been and will continue to be …
Targeting CD19 for the treatment of B-cell related autoimmune diseases with a novel T cell engager
AQ Yuan, RQ Yuan, L zhao, I Yang, L Bai, Q Meng - bioRxiv, 2024 - biorxiv.org
Autoimmune disorder, affecting more than twenty million in United States and billions of
people worldwide, occurs when human immune system mistakenly attacks its own body …
people worldwide, occurs when human immune system mistakenly attacks its own body …
Systemic administration of anti-CD20 indirectly reduces B cells in the inflamed meninges in a chronic model of central nervous system autoimmunity
Y Tesfagiorgis, EA Kemal, HC Craig, KA Parham… - Journal of …, 2024 - Elsevier
Anti-CD20 B cell depleting therapies have demonstrated that B cells are important drivers of
disease progress in Multiple Sclerosis, although the pathogenic mechanisms are not well …
disease progress in Multiple Sclerosis, although the pathogenic mechanisms are not well …