Pathogenic variants in human DNA damage repair genes mostly arose in recent human history

B Zhao, J Li, S Sinha, Z Qin, SH Kou, F Xiao, H Lei… - BMC cancer, 2024 - Springer
Background Genome stability is maintained by the DNA damage repair (DDR) system
composed of multiple DNA repair pathways of hundreds of genes. Germline pathogenic …

Assessing Platelet RNA as a Potential Biomarker for Prostate Cancer Detection

X Wang - 2024 - qmro.qmul.ac.uk
Prostate cancer (PCa) is a major carcinoma among Western men. The current prostate-
specific antigen (PSA) test has limited sensitivity and specificity, necessitating the …