From compulsivity to compulsion: the neural basis of compulsive disorders
Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a
potential transdiagnostic symptom of several neuropsychiatric disorders, including …
potential transdiagnostic symptom of several neuropsychiatric disorders, including …
Making and breaking habits: Revisiting the definitions and behavioral factors that influence habits in animals
SN Handel, RJ Smith - Journal of the Experimental Analysis of …, 2024 - Wiley Online Library
Habits have garnered significant interest in studies of associative learning and maladaptive
behavior. However, habit research has faced scrutiny and challenges related to the …
behavior. However, habit research has faced scrutiny and challenges related to the …
Developing digital interventions for a post‐Covid world: A smartphone‐based approach‐avoidance training to reduce alcohol craving
N Peerenboom, NV Guzman, T Kvamme… - Scandinavian …, 2024 - Wiley Online Library
Harmful alcohol use is a major public health issue. In‐person treatment has been hindered
by the restrictions necessary during the Covid‐19 pandemic. This study examined the effects …
by the restrictions necessary during the Covid‐19 pandemic. This study examined the effects …
[HTML][HTML] Punishment resistance for cocaine is associated with inflexible habits in rats
BO Jones, MS Paladino, AM Cruz, HF Spencer… - Addiction …, 2024 - Elsevier
Addiction is characterized by continued drug use despite negative consequences. In an
animal model, a subset of rats continues to self-administer cocaine despite footshock …
animal model, a subset of rats continues to self-administer cocaine despite footshock …
Decoupling Dopamine Synthesis from Impulsive Action, Risk-related Decision-Making, and Propensity to Cocaine Intake: A Longitudinal [18F]-FDOPA PET Study in …
G Urueña-Méndez, C Arrondeau, L Bellés, N Ginovart - Eneuro, 2024 - eneuro.org
Impulsive action and risk-related decision-making (RDM) are two facets of impulsivity linked
to a hyperdopaminergic release in the striatum and an increased propensity to cocaine …
to a hyperdopaminergic release in the striatum and an increased propensity to cocaine …
Trait impulsivity as a mediator between early cigarette smoking initiation and addiction severity in patients with methamphetamine use disorder
CY Huang, CC Hung, YJ Ho, SC Fang - International Journal of Mental …, 2024 - Springer
The prevalence of and mortality associated with methamphetamine use cause a concern. To
add insights regarding the mechanisms that drive the disease progression, we investigated …
add insights regarding the mechanisms that drive the disease progression, we investigated …
[HTML][HTML] Neurobehavioral Precursors of Compulsive Cocaine Seeking in Dual Frontostriatal Circuits
JA Jones, A Belin-Rauscent, B Jupp… - … Psychiatry Global Open …, 2024 - Elsevier
Background Only some individuals who use drugs recreationally eventually develop a
substance use disorder, characterized in part by the rigid engagement in drug foraging …
substance use disorder, characterized in part by the rigid engagement in drug foraging …
[HTML][HTML] Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks
Impulse control disorders (ICDs), a wide spectrum of maladaptive behaviors which includes
pathological gambling, hypersexuality and compulsive buying, have been recently …
pathological gambling, hypersexuality and compulsive buying, have been recently …
药物成瘾的易感性生物标记: 从神经认知到分子遗传的证据
严万森, 刘苏姣, 王露娇子 - 心理技术与应用, 2024 - xljsyyy.com
摘要药物成瘾作为一种慢性复发性的脑疾病, 具有从偶然性用药, 规律性用药到强迫性用药的
渐进式发展特征. 研究提示, 药物成瘾存在潜在的个体易感性机制, 即在成瘾发生过程中不同个体 …
渐进式发展特征. 研究提示, 药物成瘾存在潜在的个体易感性机制, 即在成瘾发生过程中不同个体 …
[HTML][HTML] Effects of access condition on substance use disorder-like phenotypes in male and female rats self-administering MDPV or cocaine
MR Doyle, NM Beltran, MSA Bushnell, M Syed… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Substance use disorder (SUD) is a heterogeneous disorder, where severity, symptoms, and
patterns of substance use vary across individuals. Yet, when rats are allowed to self …
patterns of substance use vary across individuals. Yet, when rats are allowed to self …