White adipocyte dysfunction and obesity-associated pathologies in humans
CE Hagberg, KL Spalding - Nature Reviews Molecular Cell Biology, 2024 - nature.com
The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …
worldwide, negatively impacting on societies and economies. Whereas the association …
[HTML][HTML] Cellular senescence in lung cancer: Molecular mechanisms and therapeutic interventions
Lung cancer stands as the primary contributor to cancer-related fatalities worldwide,
affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC) …
affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC) …
Sustained exposure to high glucose induces differential expression of cellular senescence markers in murine macrophages but impairs immunosurveillance response …
B Diwan, R Yadav, R Goyal, R Sharma - Biogerontology, 2024 - Springer
The influence of chronic diseases on various facets of macrophage cellular senescence is
poorly understood. This study evaluated the impact of chronic hyperglycemia on the …
poorly understood. This study evaluated the impact of chronic hyperglycemia on the …
Lipid droplets, autophagy, and ageing: a cell-specific tale
A Maestri, P Garagnani, M Pedrelli, CE Hagberg… - Ageing Research …, 2024 - Elsevier
Lipid droplets are the essential organelle for storing lipids in a cell. Within the variety of the
human body, different cells store, utilize and release lipids in different ways, depending on …
human body, different cells store, utilize and release lipids in different ways, depending on …
Combined targeting of senescent cells and senescent macrophages: a new idea for integrated treatment of lung cancer
M Gu, Y Liu, W Zheng, Z Jing, X Li, W Guo… - Seminars in cancer …, 2024 - Elsevier
Lung cancer is one of the most common cancers worldwide and a leading cause of cancer-
related deaths. Macrophages play a key role in the immune response and the tumour …
related deaths. Macrophages play a key role in the immune response and the tumour …
Longevity and anti-aging effects of curcumin supplementation
Aging is a gradual and irreversible process that is accompanied by an overall decline in
cellular function and a significant increase in the risk of age-associated disorders. Generally …
cellular function and a significant increase in the risk of age-associated disorders. Generally …
[HTML][HTML] Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection
People living with HIV (PLWH) experience increased vulnerability to premature aging and
inflammation-associated comorbidities, even when HIV replication is suppressed by …
inflammation-associated comorbidities, even when HIV replication is suppressed by …
[HTML][HTML] Macrophage senescence in health and diseases
L Wang, W Hong, H Zhu, Q He, B Yang, J Wang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Macrophage senescence, manifested by the special form of durable cell cycle arrest and
chronic low-grade inflammation like senescence-associated secretory phenotype, has long …
chronic low-grade inflammation like senescence-associated secretory phenotype, has long …
Adaptive immunity and atherosclerosis: aging at its crossroads
RPM Snijckers, AC Foks - Frontiers in immunology, 2024 - frontiersin.org
Adaptive immunity plays a profound role in atherosclerosis pathogenesis by regulating
antigen-specific responses, inflammatory signaling and antibody production. However, as …
antigen-specific responses, inflammatory signaling and antibody production. However, as …
Phytochemical Screening and Antidiabetic Efficacy of Balanites aegyptiaca Seed Extract and Their Silver Nanoparticles on Muscle and Pancreatic Cell Lines
Balanites aegyptiaca (L.) Delile, a member of the Zygophyllaceae family, is commonly
known as the desert date. This tree is famous for yielding edible fruits and is esteemed for its …
known as the desert date. This tree is famous for yielding edible fruits and is esteemed for its …