The complement system is part of innate immunity and is pivotal in protecting the body
against pathogens and maintaining host homeostasis. Activation of the complement system …

Abstract The 14th International Podocyte Conference took place in Philadelphia, USA, from
May 23rd to 26th, 2023. It commenced with an early-career researchers' meeting on May …

Uncontrolled complement activation can cause or contribute to glomerular injury in multiple
kidney diseases. While complement activation plays a causal role in atypical hemolytic …

Introduction Complement system overactivation is pivotal in lupus nephritis (LN)
pathophysiology. Considering that anti-C3 autoantibodies play a significant role in LN …

Introduction C3 glomerulopathy (C3G) is an ultrarare renal disease characterized by
deposition of complement component C3 in the glomerular basement membrane (GBM) …

Background: C3 glomerulopathy is a rare disease resulting from an overactivation of the
complement alternative pathway. Although there is also evidence of terminal pathway …

Introduction The complement system serves as a crucial defense mechanism against
invading pathogens; however, dysregulation of this system can result in harmful …

Complement factor 3 glomerulopathy (C3G) is caused by dysregulation of the alternative
complement pathway (AP), resulting in either dense deposit disease or complement factor 3 …

Résumé Les glomérulopathies à C3 sont des pathologies chroniques rares dont le
diagnostic repose sur la présence de dépôts glomérulaires prédominants de C3. Elles …

Komplementvermittelte Glomerulonephritiden (GN) werden seit dem Erscheinen der letzten
KDIGO-Leitlinie zu glomerulären Erkrankungen wieder primär in die Gruppe der GN mit …