Surviving sepsis campaign research priorities 2023

D De Backer, CS Deutschman, J Hellman… - Critical Care …, 2024 - journals.lww.com
OBJECTIVES: To identify research priorities in the management, epidemiology, outcome,
and pathophysiology of sepsis and septic shock. DESIGN: Shortly after publication of the …

Navigating the Labyrinth: Intensive Care Challenges for Patients with Acute-on-Chronic Liver Failure

FH Saner, DA Raptis, SA Alghamdi… - Journal of Clinical …, 2024 - mdpi.com
Acute-on-chronic liver failure (ACLF) refers to the deterioration of liver function in individuals
who already have chronic liver disease. In the setting of ACLF, liver damage leads to the …

Noradrenaline‐induced changes in cerebral blood flow in health, traumatic brain injury and critical illness: a systematic review with meta‐analysis

L Meng, Y Sun, X Zhao, M Rasmussen… - …, 2024 - Wiley Online Library
Background Noradrenaline is a standard treatment for hypotension in acute care. The
precise effects of noradrenaline on cerebral blood flow in health and disease remain …

[HTML][HTML] Development of a rectally administrable Dnase1 to treat septic shock by targeting NETs

SB Kwak, SJ Kim, YJ Kang, WW Lee, J Huh, JW Park - Life Sciences, 2024 - Elsevier
Aims Neutrophil extracellular trap (NET), which is formed by DNA threads, induces septic
shock by aggravating systemic inflammation. An intravenous administration of …

Treatment of Acute Kidney Injury: A Review of Current Approaches and Emerging Innovations

C Tamargo, M Hanouneh, CE Cervantes - Journal of Clinical Medicine, 2024 - mdpi.com
Acute kidney injury (AKI) is a complex and life-threatening condition with multifactorial
etiologies, ranging from ischemic injury to nephrotoxic exposures. Management is founded …

ExtraCorporeal Membrane Oxygenation in the therapy for REfractory Septic shock with Cardiac function Under Estimated (ECMO-RESCUE): study protocol for a …

W Chen, Z Guo, T Kong, W Chen, X Chen, Q Yang… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Severe septic cardiomyopathy (SCM) is one of the main causes of refractory
septic shock (RSS), with a high mortality. The application of venoarterial extracorporeal …

Blood pressure management for hypotensive patients in intensive care and perioperative cardiovascular settings

Y Kotani, JDA Ursoleo, CP Murru, G Landoni - Journal of Cardiothoracic …, 2024 - Elsevier
Blood pressure is a critical physiological parameter, particularly in the context of cardiac
intensive care and perioperative settings. As a primary indicator of organ perfusion, the …

[HTML][HTML] Protocol: ExtraCorporeal Membrane Oxygenation in the therapy for REfractory Septic shock with Cardiac function Under Estimated (ECMO-RESCUE): study …

W Chen, Z Guo, T Kong, W Chen, X Chen, Q Yang… - BMJ Open, 2024 - ncbi.nlm.nih.gov
Introduction Severe septic cardiomyopathy (SCM) is one of the main causes of refractory
septic shock (RSS), with a high mortality. The application of venoarterial extracorporeal …

Impact of premorbid use of beta‑blockers on survival outcomes of patients with sepsis: A systematic review and meta‑analysis

H Chu, F Fei, Y Su, H Zhou - Experimental and …, 2024 - spandidos-publications.com
It is unclear if premorbid use of beta‑blockers affects sepsis outcomes. The present
systematic review aimed to assess the impact of premorbid beta‑blocker use on mortality …

Analysis of the 2023 European Multidisciplinary (ESC/ESICM/EACTS) Consensus Statement on the Management of Short-term Mechanical Circulatory Support of …

KJ Augustin, PM Wieruszewski, L McLean… - … of Cardiothoracic and …, 2024 - Elsevier
Despite medical advancements, mortality in cardiogenic shock (CS) remains unacceptably
high. 1-3 The decreased cardiac output resulting in impaired oxygen delivery, characteristic …