Drosophila melanogaster Set8 and L (3) mbt function in gene expression independently of histone H4 lysine 20 methylation
AT Crain, MB Butler, CA Hill, M Huynh… - Genes & …, 2024 - genesdev.cshlp.org
Monomethylation of lysine 20 of histone H4 (H4K20me1) is catalyzed by Set8 and thought to
play important roles in many aspects of genome function that are mediated by H4K20me …
play important roles in many aspects of genome function that are mediated by H4K20me …
Histone methylation: at the crossroad between circadian rhythms in transcription and metabolism
M González-Suárez, L Aguilar-Arnal - Frontiers in Genetics, 2024 - frontiersin.org
Circadian rhythms, essential 24-hour cycles guiding biological functions, synchronize
organisms with daily environmental changes. These rhythms, which are evolutionarily …
organisms with daily environmental changes. These rhythms, which are evolutionarily …
[HTML][HTML] Unraveling the relationship between histone methylation and nonalcoholic fatty liver disease
L Xu, YH Fan, XJ Zhang, L Bai - World Journal of Hepatology, 2024 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) poses a significant health challenge in modern
societies due to shifts in lifestyle and dietary habits. Its complexity stems from genetic …
societies due to shifts in lifestyle and dietary habits. Its complexity stems from genetic …
Mono-methylated histones control PARP-1 in chromatin and transcription
PARP-1 is central to transcriptional regulation under both normal and stress conditions, with
the governing mechanisms yet to be fully understood. Our biochemical and ChIP-seq-based …
the governing mechanisms yet to be fully understood. Our biochemical and ChIP-seq-based …
PR-SET7 epigenetically restrains uterine interferon response and cell death governing proper postnatal stromal development
H Bao, Y Sun, N Deng, L Zhang, Y Jia, G Li… - Nature …, 2024 - nature.com
The differentiation of the stroma is a hallmark event during postnatal uterine development.
However, the spatiotemporal changes that occur during this process and the underlying …
However, the spatiotemporal changes that occur during this process and the underlying …
Endonucleosis mediates internalization of cytoplasm into the nucleus
O Galanopoulou, EC Tachmatzidi, E Deligianni… - Nature …, 2024 - nature.com
Setd8 regulates transcription elongation, mitotic DNA condensation, DNA damage response
and replication licensing. Here we show that, in mitogen-stimulated liver-specific Setd8-KO …
and replication licensing. Here we show that, in mitogen-stimulated liver-specific Setd8-KO …
[HTML][HTML] Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription
HM Scott, MH Smith, AK Coleman, KS Armijo… - Cell reports, 2024 - cell.com
Tight regulation of macrophage immune gene expression is required to fight infection
without risking harmful inflammation. The contribution of RNA-binding proteins (RBPs) to …
without risking harmful inflammation. The contribution of RNA-binding proteins (RBPs) to …
Chromosomal copy number amplification-driven Linc01711 contributes to gastric cancer progression through histone modification-mediated reprogramming of …
B Yue, J Chen, T Bao, Y Zhang, L Yang, Z Zhang… - Gastric Cancer, 2024 - Springer
Background Chromosome gains or localized amplifications are frequently observed in
human gastric cancer (GC) and are major causes of aberrant oncogene activation. However …
human gastric cancer (GC) and are major causes of aberrant oncogene activation. However …
Mono-methylated histones control PARP-1 in chromatin and transcription
B Gbolahan, B Guillaume, L Niraj, T Alexei - eLife, 2024 - search.proquest.com
PARP-1 is central to transcriptional regulation under both normal and stress conditions, with
the governing mechanisms yet to be fully understood. Our biochemical and ChIP-seq-based …
the governing mechanisms yet to be fully understood. Our biochemical and ChIP-seq-based …