Summary Each year, an estimated 7· 7 million deaths are attributed to bacterial infections, of
which 4.95 million are associated with drug-resistant pathogens, and 1· 27 million are …

Salmonella Typhi, the invasive serovar of S. enterica subspecies enterica, causes typhoid
fever in healthy human hosts. The emergence of antibiotic‐resistant strains has consistently …

Background Enteric fever, a systemic infection caused by Salmonella enterica serovars
Typhi and Paratyphi A, remains a major cause of morbidity and mortality in low-income and …

Background Randomised controlled trials of typhoid conjugate vaccines among children in
Africa and Asia have shown high short-term efficacy. Data on the durability of protection …

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The pharmacological potential of the pyrazole moiety is demonstrated by their presence in a
wide range of therapeutic agents spanning various categories. Notable examples include …

Background Ciprofloxacin is the first-line drug for treating typhoid fever in many countries in
Africa with a high disease burden, but the emergence of non-susceptibility poses a …

The emergence of multi-drug resistance in Salmonella, causing food-borne infections, is a
significant issue. With over 2,600 serovars in in Salmonella sp., it is crucial to identify specific …

Background Typhoid fever is a common cause of febrile illness in low-and middle-income
countries. While multidrug-resistant (MDR) Salmonella Typhi (S. Typhi) has spread globally …

Tomatoes are readily available and affordable vegetables that offer a range of health
benefits due to their bioactive molecules, such as antioxidants and antimicrobials. In contrast …