Local and systemic mechanisms that control the hair follicle stem cell niche
B Zhang, T Chen - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Hair follicles are essential appendages of the mammalian skin, as hair performs vital
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …
Unleashing Axonal Regeneration Capacities: Neuronal and Non-neuronal Changes After Injuries to Dorsal Root Ganglion Neuron Central and Peripheral Axonal …
Q Zhao, C Jiang, L Zhao, X Dai, S Yi - Molecular Neurobiology, 2024 - Springer
Peripheral nerves obtain remarkable regenerative capacity while central nerves can hardly
regenerate following nerve injury. Sensory neurons in the dorsal root ganglion (DRG) are …
regenerate following nerve injury. Sensory neurons in the dorsal root ganglion (DRG) are …
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are
specialized to detect and transduce diverse environmental stimuli to the central nervous …
specialized to detect and transduce diverse environmental stimuli to the central nervous …
[HTML][HTML] A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes
Dorsal root ganglia (DRG) somatosensory neurons detect mechanical, thermal, and
chemical stimuli acting on the body. Achieving a holistic view of how different DRG neuron …
chemical stimuli acting on the body. Achieving a holistic view of how different DRG neuron …
Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn
MA Gradwell, N Ozeri-Engelhard, JT Eisdorfer… - Neuron, 2024 - cell.com
Sensory feedback is integral for contextually appropriate motor output, yet the neural circuits
responsible remain elusive. Here, we pinpoint the medial deep dorsal horn of the mouse …
responsible remain elusive. Here, we pinpoint the medial deep dorsal horn of the mouse …
[HTML][HTML] Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons
How mechanical allodynia following nerve injury is encoded in patterns of neural activity in
the spinal cord dorsal horn (DH) remains incompletely understood. We address this in mice …
the spinal cord dorsal horn (DH) remains incompletely understood. We address this in mice …
[HTML][HTML] A review of dorsal root ganglia and primary sensory neuron plasticity mediating inflammatory and chronic neuropathic pain
K Jang, SM Garraway - Neurobiology of Pain, 2024 - Elsevier
Pain is a sensory state resulting from complex integration of peripheral nociceptive inputs
and central processing. Pain consists of adaptive pain that is acute and beneficial for …
and central processing. Pain consists of adaptive pain that is acute and beneficial for …
[HTML][HTML] Distinct local and global functions of mouse Aβ low-threshold mechanoreceptors in mechanical nociception
M Gautam, A Yamada, AI Yamada, Q Wu… - nature …, 2024 - nature.com
The roles of Aβ low-threshold mechanoreceptors (LTMRs) in transmitting mechanical
hyperalgesia and in alleviating chronic pain have been of great interest but remain …
hyperalgesia and in alleviating chronic pain have been of great interest but remain …
GPR39 regulated spinal glycinergic inhibition and mechanical inflammatory pain
HH Bai, KL Wang, XR Zeng, J Li, Y Li, JY Xu… - Science …, 2024 - science.org
G protein–coupled receptor 39 (GPR39) senses the change of extracellular divalent zinc ion
and signals through multiple G proteins to a broad spectrum of downstream effectors. Here …
and signals through multiple G proteins to a broad spectrum of downstream effectors. Here …
[HTML][HTML] Krause corpuscles are genital vibrotactile sensors for sexual behaviours
Krause corpuscles, which were discovered in the 1850s, are specialized sensory structures
found within the genitalia and other mucocutaneous tissues,,–. The physiological properties …
found within the genitalia and other mucocutaneous tissues,,–. The physiological properties …