Hair follicles are essential appendages of the mammalian skin, as hair performs vital
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …

Peripheral nerves obtain remarkable regenerative capacity while central nerves can hardly
regenerate following nerve injury. Sensory neurons in the dorsal root ganglion (DRG) are …

Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are
specialized to detect and transduce diverse environmental stimuli to the central nervous …

Dorsal root ganglia (DRG) somatosensory neurons detect mechanical, thermal, and
chemical stimuli acting on the body. Achieving a holistic view of how different DRG neuron …

Sensory feedback is integral for contextually appropriate motor output, yet the neural circuits
responsible remain elusive. Here, we pinpoint the medial deep dorsal horn of the mouse …

How mechanical allodynia following nerve injury is encoded in patterns of neural activity in
the spinal cord dorsal horn (DH) remains incompletely understood. We address this in mice …

Pain is a sensory state resulting from complex integration of peripheral nociceptive inputs
and central processing. Pain consists of adaptive pain that is acute and beneficial for …

The roles of Aβ low-threshold mechanoreceptors (LTMRs) in transmitting mechanical
hyperalgesia and in alleviating chronic pain have been of great interest but remain …

G protein–coupled receptor 39 (GPR39) senses the change of extracellular divalent zinc ion
and signals through multiple G proteins to a broad spectrum of downstream effectors. Here …

Krause corpuscles, which were discovered in the 1850s, are specialized sensory structures
found within the genitalia and other mucocutaneous tissues,,–. The physiological properties …