[HTML][HTML] Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously
M Guo, J Wu, C Chen, X Wang, A Gong, W Guan… - Nature …, 2024 - nature.com
Human naïve pluripotent stem cells (hnPSCs) can generate integrated models of blastocysts
termed blastoids upon switch to inductive medium. However, the underlying mechanisms …
termed blastoids upon switch to inductive medium. However, the underlying mechanisms …
[HTML][HTML] The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development
D Saha, S Animireddy… - Biochemical Society …, 2024 - portlandpress.com
ATP dependent chromatin remodelers have pivotal roles in transcription, DNA replication
and repair, and maintaining genome integrity. SWI/SNF remodelers were first discovered in …
and repair, and maintaining genome integrity. SWI/SNF remodelers were first discovered in …
The MEK-ERK signaling pathway promotes maintenance of cardiac chamber identity
Y Yao, D Gupta, D Yelon - Development, 2024 - journals.biologists.com
Ventricular and atrial cardiac chambers have unique structural and contractile
characteristics that underlie their distinct functions. The maintenance of chamber-specific …
characteristics that underlie their distinct functions. The maintenance of chamber-specific …
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
Studies in the mouse demonstrate the importance of fibroblast growth factor (FGF) and extra-
cellular receptor tyrosine kinase (ERK) in specification of embryo-fated epiblast and yolk-sac …
cellular receptor tyrosine kinase (ERK) in specification of embryo-fated epiblast and yolk-sac …
Efficient derivation of embryonic stem cells and primordial germ cell-like cells in cattle
A Shirasawa, M Hayashi, M Shono, A Ideta… - … of Reproduction and …, 2024 - jstage.jst.go.jp
The induction of the germ cell lineage from pluripotent stem cells (in vitro gametogenesis)
will help understand the mechanisms underlying germ cell differentiation and provide an …
will help understand the mechanisms underlying germ cell differentiation and provide an …
Unraveling the function of FGF signaling in human hypoblast specialization
H Wu, J Zhai, H Wang - Cell Stem Cell, 2024 - Elsevier
Unraveling the function of FGF signaling in human hypoblast specialization - ScienceDirect
Skip to main contentSkip to article Elsevier logo Journals & Books Help Search My account …
Skip to main contentSkip to article Elsevier logo Journals & Books Help Search My account …
MEK signalling pathway is required for hypoblast specification and migration in ovine
NM de Los Reyes, I Flores-Borobia… - …, 2024 - rep.bioscientifica.com
In brief MEK signalling pathway is required for hypoblast differentiation in mouse embryos,
but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is …
but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is …
The progress of induced pluripotent stem cells derived from pigs: a mini review of recent advances
JA Neira, JV Conrad, M Rusteika… - Frontiers in Cell and …, 2024 - frontiersin.org
Pigs (Sus scrofa) are widely acknowledged as an important large mammalian animal model
due to their similarity to human physiology, genetics, and immunology. Leveraging the full …
due to their similarity to human physiology, genetics, and immunology. Leveraging the full …
In vitro generation of trophoblast like stem cells from goat pluripotent stem cells
Q Na, S Zhang, P Shao, Y Jia, Y Wang, M Wei, Y Chen… - Theriogenology, 2024 - Elsevier
Since the first mouse induced pluripotent stem cells (iPSCs) was derived, the in vitro culture
of domestic iPSCs functionally and molecularly comparable with mouse iPSCs has been a …
of domestic iPSCs functionally and molecularly comparable with mouse iPSCs has been a …