The dense extracellular matrix (ECM) in the pancreatic cancer severely hampers the
penetration of nanodrugs, which causes inferior therapeutic efficacy. To address this issue, a …

The high malignant degree and poor prognosis of pancreatic cancer (PC) pose severe
challenges to the basic research and clinical translation of next-generation therapies. The …

Circulating extracellular matrix (ECM) proteins are serological biomarkers of interest due to
their association with pathologies involving disease processes such as fibrosis and cancers …

Postbiotics are produced by microbes and have recently gained importance in the field of
oncology due to their beneficial effects to the host, effectiveness against cancer cells, and …

Pancreatic ductal adenocarcinoma (PDAC) presents a formidable clinical challenge due to
its intricate microenvironment characterized by desmoplasia and complex tumor-stroma …

The glycosaminoglycan hyaluronan (HA) plays an important role in tumor progression.
However, its biological and clinical significance in papillary thyroid cancer (PTC) remains …

Background and aims The N-terminal propeptide of type III collagen (PRO-C3) assay
measures a pro-peptide released during type III collagen synthesis, an important feature of …

Chronic pancreatitis (CP) is the end-stage of continuous inflammation and fibrosis in the
pancreas evolving from acute-to recurrent acute-, early, and, finally, end-stage CP …

Disclosed herein are monoclonal antibodies that specifically recognise and bind to a C-
terminus of a peptide that is the C-terminus neo-epitope formed on cleavage of the N …