Remyelination in the Central Nervous System
RJM Franklin, B Bodini… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The inability of the mammalian central nervous system (CNS) to undergo spontaneous
regeneration has long been regarded as a central tenet of neurobiology. However, while this …
regeneration has long been regarded as a central tenet of neurobiology. However, while this …
Cerebral White Matter Alterations Associated With Oligodendrocyte Vulnerability in Organic Acidurias: Insights in Glutaric Aciduria Type I
The white matter is an important constituent of the central nervous system, containing axons,
oligodendrocytes, and its progenitor cells, astrocytes, and microglial cells. Oligodendrocytes …
oligodendrocytes, and its progenitor cells, astrocytes, and microglial cells. Oligodendrocytes …
Astrocytic TIMP-1 regulates production of Anastellin, an inhibitor of oligodendrocyte differentiation and FTY720 responses
Astrocyte activation is associated with neuropathology and the production of tissue inhibitor
of metalloproteinase-1 (TIMP1). TIMP1 is a pleiotropic extracellular protein that functions …
of metalloproteinase-1 (TIMP1). TIMP1 is a pleiotropic extracellular protein that functions …
Relationship between astrocytic reactivity and white matter integrity in the context of Alzheimer's disease pathologies
Astrocytes exhibit reactive responses to various brain pathologies, including Alzheimer's
Disease (AD), which can have both adaptive and maladaptive effects on brain function …
Disease (AD), which can have both adaptive and maladaptive effects on brain function …