CD-MOFs: From preparation to drug delivery and therapeutic application

Y Si, H Luo, P Zhang, C Zhang, J Li, P Jiang… - Carbohydrate …, 2024 - Elsevier
Cyclodextrin metal-organic frameworks (CD-MOFs) show considerable advantages of
edibility, degradability, low toxicity, and high drug loading, which have attracted enormous …

Molecular mechanisms and therapeutic potential of lithium in Alzheimer's disease: repurposing an old class of drugs

Y Shen, M Zhao, P Zhao, L Meng, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline and memory loss. Despite advances in understanding the …

Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease

FAY Yengej, CP Casellas, CME Ammerlaan… - Cell Reports, 2024 - cell.com
Organoid technology is rapidly gaining ground for studies on organ (patho) physiology.
Tubuloids are long-term expanding organoids grown from adult kidney tissue or urine. The …

Occupational, environmental, and toxicological health risks of mining metals for lithium-ion batteries: a narrative review of the Pubmed database

CW Brown, CE Goldfine, LT Allan-Blitz… - Journal of Occupational …, 2024 - Springer
Background The global market for lithium-ion batteries (LIBs) is growing exponentially,
resulting in an increase in mining activities for the metals needed for manufacturing LIBs …

New advances in the pharmacology and toxicology of lithium: a neurobiologically oriented overview

A Bortolozzi, G Fico, M Berk, M Solmi, M Fornaro… - Pharmacological …, 2024 - ASPET
Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

Association between lithium treatment and renal, thyroid and parathyroid function: a cohort study of 6659 patients with bipolar disorder

AC Wiuff, C Rohde, BD Jensen… - Bipolar …, 2024 - Wiley Online Library
Objectives Although potential adverse effects of lithium treatment on renal and endocrine
systems have been extensively investigated, most prior studies are limited by selected …

Safety of psychotropic medications in pregnancy: an umbrella review

N Fabiano, S Wong, A Gupta, J Tran, N Bhambra… - Molecular …, 2024 - nature.com
Weighing risks and benefits of the use of psychotropic medications during pregnancy
remains a challenge worldwide. We systematically assessed the strength of associations …

The Changes of Blood and CSF Ion Levels in Depressed Patients: a Systematic Review and Meta-analysis

Y Meng, S Liu, M Yu, H Liang, Y Tong, J Song… - Molecular …, 2024 - Springer
Micronutrient deficiencies and excesses are closely related to developing and treating
depression. Traditional and effective antidepressants include tricyclic antidepressants …

Lithium Pollution and Its Associated Health Risks in the Largest Lithium Extraction Industrial Area in China

X Yang, H Wen, Y Liu, Y Huang, Q Zhang… - Environmental …, 2024 - ACS Publications
Lithium (Li) is an important resource that drives sustainable mobility and renewable energy.
Its demand is projected to continue to increase in the coming decades. However, the risk of …

Clinical and genetic contributions to medical comorbidity in bipolar disorder: a study using electronic health records-linked biobank data

JA Sanchez-Ruiz, BJ Coombes, VM Pazdernik… - Molecular …, 2024 - nature.com
Bipolar disorder is a chronic and complex polygenic disease with high rates of comorbidity.
However, the independent contribution of either diagnosis or genetic risk of bipolar disorder …