Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double …
HA Ghofrani, G Simonneau, AM D'Armini… - The Lancet …, 2024 - thelancet.com
Background Macitentan is beneficial for long-term treatment of pulmonary arterial
hypertension. The microvasculopathy of chronic thromboembolic pulmonary hypertension …
hypertension. The microvasculopathy of chronic thromboembolic pulmonary hypertension …
Insights into the relationship between serum uric acid and pulmonary hypertension
Y Zhou, M Chen, J Zheng, X Shui… - Molecular …, 2024 - spandidos-publications.com
Pulmonary hypertension (PH) is a progressive lethal disease, which is characterized by
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …
Recent developments in dry powder inhalation (DPI) formulations for lung-targeted drug delivery
Background Dry powder inhalation (DPI) formulations have been widely studied for the
treatment of respiratory diseases, including COVID-19, which have become common and …
treatment of respiratory diseases, including COVID-19, which have become common and …
Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is characterised by pulmonary vascular remodelling
causing premature death from right heart failure. Established DNA variants influence PAH …
causing premature death from right heart failure. Established DNA variants influence PAH …
Clinical and prognostic implications of right ventricular uptake on bone scintigraphy in transthyretin amyloid cardiomyopathy
A Porcari, M Fontana, M Canepa, E Biagini, F Cappelli… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The extent of myocardial bone tracer uptake with technetium
pyrophosphate, hydroxymethylene diphosphonate, and 3, 3-diphosphono-1, 2 …
pyrophosphate, hydroxymethylene diphosphonate, and 3, 3-diphosphono-1, 2 …
[HTML][HTML] Whole-heart modelling with valves in a fluid–structure interaction framework
Computational modelling of whole-heart function is a useful tool to study heart mechanics
and haemodynamics. Many existing heart models focus on electromechanical aspect …
and haemodynamics. Many existing heart models focus on electromechanical aspect …
Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation
Aims Pulmonary hypertension (PH) is a pulmonary vascular disease characterized by a high
mortality rate. Pulmonary arterial endothelium cells (PAECs) serve as a primary sensor of …
mortality rate. Pulmonary arterial endothelium cells (PAECs) serve as a primary sensor of …
Functional capacity and dyspnea during follow-up after acute pulmonary embolism
Background Dissecting the determinants of functional capacity during long-term follow-up
after acute pulmonary embolism (PE) can help to better characterize a patient population …
after acute pulmonary embolism (PE) can help to better characterize a patient population …
Machine Learning for Diagnosis of Pulmonary Hypertension by Echocardiography
V Anand, AD Weston, CG Scott, GC Kane… - Mayo Clinic …, 2024 - Elsevier
Objective To evaluate a machine learning (ML)–based model for pulmonary hypertension
(PH) prediction using measurements and impressions made during echocardiography …
(PH) prediction using measurements and impressions made during echocardiography …
Dual-layer dual-energy CT-derived pulmonary perfusion for the differentiation of acute pulmonary embolism and chronic thromboembolic pulmonary hypertension
RJ Gertz, F Gerhardt, M Pienn, S Lennartz… - European …, 2024 - Springer
Objectives To evaluate dual-layer dual-energy computed tomography (dlDECT)–derived
pulmonary perfusion maps for differentiation between acute pulmonary embolism (PE) and …
pulmonary perfusion maps for differentiation between acute pulmonary embolism (PE) and …