Functional Roles of CD26/DPP4 in Bleomycin-Induced Pulmonary Hypertension Associated with Interstitial Lung Disease

T Okaya, T Kawasaki, S Sato, Y Koyanagi… - International Journal of …, 2024 - mdpi.com
Pulmonary hypertension (PH) with interstitial lung diseases (ILDs) often causes intractable
conditions. CD26/Dipeptidyl peptidase-4 (DPP4) is expressed in lung constituent cells and …

Transcriptional Responses of Different Brain Cell Types to Oxygen Decline

C Ravel-Godreuil, ER Roy, SN Puttapaka, S Li, Y Wang… - Brain Sciences, 2024 - mdpi.com
Brain hypoxia is associated with a wide range of physiological and clinical conditions.
Although oxygen is an essential constituent of maintaining brain functions, our …

Blockage of the adenosine A2B receptor prevents cardiac fibroblasts overgrowth in rats with pulmonary arterial hypertension

M Bessa-Gonçalves, B Bragança, E Martins-Dias… - Purinergic …, 2024 - Springer
Sustained pressure overload and fibrosis of the right ventricle (RV) are the leading causes of
mortality in pulmonary arterial hypertension (PAH). Although the role of adenosine in PAH …

Screening and toxicity evaluation of natural compounds as adenosine 2a and 2b receptor ligands: insights from molecular docking, dynamics, and ADMET analysis

F Karakuş, MA Alagöz, B Kuzu - Drug and Chemical Toxicology, 2024 - Taylor & Francis
Recent studies suggest that immunological and inflammatory responses in cardiovascular
disorders, such as hypertension, myocardial infarction, ischemia injury, heart failure …

Untersuchung des Einflusses des Adenosin-Rezeptors 2b auf die Signaltransduktion sowie den Metabolismus von Plattenepithelkarzinom-Zellen des Kopf-Hals …

J Dünser - 2024 - oparu.uni-ulm.de
Die hier vorliegende Arbeit befasst sich mit der Rolle von Adenosin in
Plattenepithelkarzinomzellen des Kopf-Halsbereichs, insbesondere die Wechselwirkung mit …