[HTML][HTML] Methodology for awakening the potential secondary metabolic capacity in actinomycetes
Secondary metabolites produced by actinomycete strains undoubtedly have great potential
for use in applied research areas such as drug discovery. However, it is becoming difficult to …
for use in applied research areas such as drug discovery. However, it is becoming difficult to …
Industrial and Pharmaceutical Applications of Microbial Diversity of Hypersaline Ecology from Lonar Soda Crater
The unidentified geochemical and physiochemical characteristics of Soda Lakes across the
globe make it a novel reservoir and bring attention to scientific civic for its conceivable …
globe make it a novel reservoir and bring attention to scientific civic for its conceivable …
[HTML][HTML] Discovery of the Pendulisporaceae: An extremotolerant myxobacterial family with distinct sporulation behavior and prolific specialized metabolism
R Garcia, A Popoff, CD Bader, J Löhr, S Walesch… - Chem, 2024 - cell.com
Myxococcota represents a small bacterial phylum comprising seven families, which have
been shown to be exceptionally rich producers of pharmaceutically interesting natural …
been shown to be exceptionally rich producers of pharmaceutically interesting natural …
Biosynthesis of novel desferrioxamine derivatives requires unprecedented crosstalk between separate NRPS-independent siderophore pathways
L Su, Y Souaibou, L Hôtel, C Paris… - Applied and …, 2024 - Am Soc Microbiol
Iron is essential to many biological processes but its poor solubility in aerobic environments
restricts its bioavailability. To overcome this limitation, bacteria have evolved a variety of …
restricts its bioavailability. To overcome this limitation, bacteria have evolved a variety of …
Functional antagonism and insights into the biosynthetic potential of human gut-derived microbes
The specialised small molecules encoded by commensal microbes mediate distinct
functional interactions. However, there is a landscape of antagonistic interactions mediated …
functional interactions. However, there is a landscape of antagonistic interactions mediated …
[HTML][HTML] A Genomics-Based Discovery of Secondary Metabolite Biosynthetic Gene Clusters in the Potential Novel Strain Streptomyces sp. 21So2-11 Isolated from …
Y Du, W Han, P Hao, Y Hu, T Hu, Y Zeng - Microorganisms, 2024 - mdpi.com
Streptomyces species are attractive sources of secondary metabolites that serve as major
sources of antibiotics and other drugs. In this study, genome mining was used to determine …
sources of antibiotics and other drugs. In this study, genome mining was used to determine …
Genomes and secondary metabolomes of Streptomyces spp. isolated from Leontopodium nivale ssp. alpinum
F Malfent, M Zehl, RH Kirkegaard… - Frontiers in …, 2024 - frontiersin.org
Bacterial endophytes dwelling in medicinal plants represent an as yet underexplored source
of bioactive natural products with the potential to be developed into drugs against various …
of bioactive natural products with the potential to be developed into drugs against various …