Melatonin, the 'hormone of darkness' is a neuronal hormone secreted by the pineal gland
and other extra pineal sites. Responsible for the circadian rhythm and seasonal behaviour of …

Osteoporotic bone defects, a severe complication of osteoporosis, are distinguished by a
delayed bone healing process and poor repair quality. While bone marrow‐derived …

Fibrosis, the excessive deposition of fibrous connective tissue in an organ in response to
injury, is a pathological condition affecting many individuals worldwide. Fibrosis causes the …

Abstract Environmental aflatoxin B 1 (AFB 1) exposure has been proposed to contribute to
hepatocellular carcinoma by promoting liver fibrosis, but the potential mechanisms remain to …

Nonalcoholic steatohepatitis (NASH) is emerging as a major cause of liver transplantation
and hepatocellular carcinoma (HCC). Regrettably, its pathological mechanisms are still not …

Background Negative energy balance (NEB) typically occurs in dairy cows after delivery.
Cows with a high yield are more likely to experience significant NEB. This type of metabolic …

Abstract Background and Aim Mitochondrial quality control (MQC) plays a significant role in
the progression of liver fibrosis, with key processes such as mitochondrial fission, fusion …

The elevated level of hepatic oxidative stress (OS) in polycystic ovary syndrome (PCOS) is
one of the important causes of liver abnormalities. Therefore, decreasing the level of hepatic …

Adiponectin plays key roles in energy metabolism and ameliorates inflammation, oxidative
stress, and mitochondrial dysfunction via its primary receptors, adiponectin receptors− 1 and …

肝纤维化是机体对各种因素诱导的慢性病肝损伤进行的修复愈合反应, 与肝硬化,
肝癌的发生存在一定关系, 阻止或逆转肝纤维化对于减少肝硬化和肝癌的发生至关重要 …