Biofilm-mediated infections by multidrug-resistant microbes: A comprehensive exploration and forward perspectives

MM Zafer, GA Mohamed, SRM Ibrahim, S Ghosh… - Archives of …, 2024 - Springer
A biofilm is a collection of microorganisms organized in a matrix of extracellular polymeric
material. Biofilms consist of microbial cells that attach to both surfaces and each other …

Bacterial aggregation triggered by low-level antibiotic-mediated lysis

S Tavaddod, A Dawson, RJ Allen - npj Biofilms and Microbiomes, 2024 - nature.com
Suspended bacterial aggregates play a central role in ocean biogeochemistry, industrial
processes and probably many clinical infections–yet the factors that trigger aggregation …

Molecular mechanism of Hfq-dependent sRNA1039 and sRNA1600 regulating antibiotic resistance and virulence in Shigella sonnei

Y Du, Y Wang, J Geng, J Long, H Yang, G Duan… - International Journal of …, 2024 - Elsevier
Bacillary dysentery caused by Shigella spp. is a significant concern for human health. Small
non-coding RNA (sRNA) plays a crucial role in regulating antibiotic resistance and virulence …

Beyond antibiotics: CRISPR/Cas9 triumph over biofilm-associated antibiotic resistance infections

A Zuberi, N Ahmad, H Ahmad, M Saeed… - Frontiers in Cellular and …, 2024 - frontiersin.org
A complex structure known as a biofilm is formed when a variety of bacterial colonies or a
single type of cell in a group sticks to a surface. The extracellular polymeric compounds that …

Perspectives on antimicrobial properties of Paulownia tomentosa Steud. fruit products in the control of Staphylococcus aureus infections

G Škovranová, L Molčanová, B Jug, D Jug… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Paulownia tomentosa Steud.(P. tomentosa) is a
medium-sized tree traditionally used in Chinese folk medicine for the treatment of infectious …

[HTML][HTML] Antimicrobial hydrogel foam dressing with controlled release of gallium maltolate for infection control in chronic wounds

Z Lan, L Guo, A Fletcher, N Ang, C Whitfield-Cargile… - Bioactive Materials, 2024 - Elsevier
Effective treatment of infection in chronic wounds is critical to improve patient outcomes and
prevent severe complications, including systemic infections, increased morbidity, and …

Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress …

Y Chekli, S Thiriet-Rupert, C Caillet, F Quilès… - Nanoscale, 2024 - pubs.rsc.org
The ability of bacteria to interact with their environment is crucial to form aggregates and
biofilms, and develop a collective stress resistance behavior. Despite its environmental and …

Pseudomonas aeruginosa Activates Quorum Sensing, Antioxidant Enzymes and Type VI Secretion in Response to Oxidative Stress to Initiate Biofilm Formation and …

JH Kim, J Dong, BH Le, ZR Lonergan, W Gu, T Girke… - Antioxidants, 2024 - mdpi.com
Pseudomonas aeruginosa (PA) is an opportunistic pathogen frequently isolated from
cutaneous chronic wounds. How PA, in the presence of oxidative stress (OS), colonizes …

[HTML][HTML] Antibiofilm activity of Prevotella species from the cystic fibrosis lung microbiota against Pseudomonas aeruginosa

L Grassi, KL Asfahl, S Van den Bossche, I Maenhout… - Biofilm, 2024 - Elsevier
It is increasingly recognized that interspecies interactions may modulate the pathogenicity of
Pseudomonas aeruginosa during chronic lung infections. Nevertheless, while the interaction …

Neutralizing Staphylococcus aureus PAMPs that Trigger Cytokine Release from THP-1 Monocytes

N Heydarian, M Ferrell, AS Nair, C Roedl, Z Peng… - ACS …, 2024 - ACS Publications
Innate immunity has considerable specificity and can discriminate between individual
species of microbes. In this regard, pathogens are “seen” as dangerous to the host and elicit …