[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

[HTML][HTML] Engineered smart materials for RNA based molecular therapy to treat Glioblastoma

RR Singh, I Mondal, T Janjua, A Popat… - Bioactive Materials, 2024 - Elsevier
Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that
remains incurable despite the multitude of improvements in cancer therapeutics. The …

A review of approaches to potentiate the activity of temozolomide against glioblastoma to overcome resistance

AS Karve, JM Desai, SN Gadgil, N Dave… - International Journal of …, 2024 - mdpi.com
A glioblastoma (GBM) is one of the most aggressive, infiltrative, and treatment-resistant
malignancies of the central nervous system (CNS). The current standard of care for GBMs …

[HTML][HTML] Advances in the Use of Chitosan and Chlorotoxin-Functionalized Chitosan Polymers in Drug Delivery and Detection of Glioma-A Review

M Wiranowska - Carbohydrate Polymer Technologies and Applications, 2024 - Elsevier
The focus of this review is on chitosan and the functionalization of chitosan nanoparticles
using chlorotoxin as a targeting agent in drug delivery and treatment of glioma. Chitosan has …

[HTML][HTML] Improving Glioma Drug Delivery: A Multifaceted Approach for Glioma Drug Development

MG Yonk, MA Lim, CM Thompson, MS Tora… - Pharmacological …, 2024 - Elsevier
Glioma is one of the most common central nervous system (CNS) cancers that can be found
within the brain and the spinal cord. One of the pressing issues plaguing the development of …

Intertumoral and intratumoral barriers as approaches for drug delivery and theranostics to solid tumors using stimuli-responsive materials

KK Chenab, H Malektaj, AAR Nadinlooie… - Microchimica Acta, 2024 - Springer
The solid tumors provide a series of biological barriers in cellular microenvironment for
designing drug delivery methods based on advanced stimuli-responsive materials. These …

Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel Treatments

G Hovis, N Chandra, N Kejriwal, KJY Hsieh… - International Journal of …, 2024 - mdpi.com
Glioblastoma is a highly aggressive neoplasm and the most common primary malignant
brain tumor. Endothelial tissue plays a critical role in glioblastoma growth and progression …

Temozolomide nano-in-nanofiber delivery system with sustained release and enhanced cellular uptake by U87MG cells

K Shetty, KS Yadav - Drug Development and Industrial Pharmacy, 2024 - Taylor & Francis
Objective The study was aimed at formulating temozolomide (TMZ) loaded gelatin
nanoparticles (GNPs) encapsulated into polyvinyl alcohol (PVA) nanofibers (TMZ–GNPs …

Magnet-Guided Temozolomide and Ferucarbotran Loaded Nanoparticles to Enhance Therapeutic Efficacy in Glioma Model

RG Thomas, S Kim, TAT Tran, YH Kim, R Nagareddy… - Nanomaterials, 2024 - mdpi.com
Background. The aim of the study was to synthesize liposomal nanoparticles loaded with
temozolomide and ferucarbotran (LTF) and to evaluate the theranostic effect of LTF in the …