How does a fly die? Insights into ageing from the pathophysiology of Drosophila mortality
E Dos Santos, HM Cochemé - GeroScience, 2024 - Springer
The fruit fly Drosophila melanogaster is a common animal model in ageing research. Large
populations of flies are used to study the impact of genetic, nutritional and pharmacological …
populations of flies are used to study the impact of genetic, nutritional and pharmacological …
Mechanistic characterization of a Drosophila model of paraneoplastic nephrotic syndrome
Paraneoplastic syndromes occur in cancer patients and originate from dysfunction of organs
at a distance from the tumor or its metastasis. A wide range of organs can be affected in …
at a distance from the tumor or its metastasis. A wide range of organs can be affected in …
Zn-CD@ Eu Ratiometric Fluorescent Probe for the Detection of Dipicolinic Acid, Uric Acid, and Ex Vivo Uric Acid Imaging
U Mohapatro, L Mishra, M Mishra… - Analytical …, 2024 - ACS Publications
Development of reliable methods for the detection of potential biomarkers is of the utmost
importance for an early diagnosis of critical diseases and disorders. In this study, a novel …
importance for an early diagnosis of critical diseases and disorders. In this study, a novel …
Altering heparan sulfate suppresses cell abnormalities and neuron loss in Drosophila presenilin model of Alzheimer Disease
N Schultheis, A Connell, A Kapral, RJ Becker… - iScience, 2024 - cell.com
We examined the function of heparan-sulfate-modified proteoglycans (HSPGs) in pathways
affecting Alzheimer disease (AD)-related cell pathology in human cell lines and mouse …
affecting Alzheimer disease (AD)-related cell pathology in human cell lines and mouse …
Dietary protein level influences growth, adult emergence, and susceptibility to bacterial infection in Hermetia illucens L.(Diptera: Stratiomyidae) larvae
The larvae of the black soldier fly (BSFL), Hermetia illucens L.(Diptera: Stratiomyidae), are
grown on diverse residual organic matter that differ in their protein content and contain a …
grown on diverse residual organic matter that differ in their protein content and contain a …
A Nonsecretory Antimicrobial Peptide Mediates Inflammatory Organ Damage in Drosophila Renal Tubules
A Oi, S Nagashima, N Shinoda, M Miura, F Obata - bioRxiv, 2024 - biorxiv.org
An excessive immune response damages organs, yet its molecular mechanism is
incompletely understood. In this study, we used Drosophila renal tubules as a model to …
incompletely understood. In this study, we used Drosophila renal tubules as a model to …
Heparan sulfate modified proteins affect cellular processes central to neurodegeneration and modulate presenilin function
N Schultheis, A Connell, A Kapral, RJ Becker… - bioRxiv, 2024 - biorxiv.org
Mutations in presenilin-1 (PSEN1) are the most common cause of familial, early-onset
Alzheimer's disease (AD), typically producing cognitive deficits in the fourth decade. A …
Alzheimer's disease (AD), typically producing cognitive deficits in the fourth decade. A …