Cardiovascular Concerns, Cancer Treatment, and Biological and Chronological Aging in Cancer: JACC Family Series

D Ioffe, SC Bhatia-Patel, S Gandhi, EA Hamad, E Dotan - Cardio Oncology, 2024 - jacc.org
Cardiovascular disease (CVD) and cancer are leading causes of death globally, particularly
among the rapidly growing population of older adults (OAs). CVD is a leading cause of …

More drugs versus more data: the tug of war on cancer in low-and middle-income countries

M Chamberlin, C Booth, GA Brooks… - Hematology …, 2024 - hemonc.theclinics.com
In June 2016, the chief executive office of a large pharmaceutical company stated “Giving
out free cancer drugs will not help the poorest parts of Africa”. 1 The investigator advocated …

[HTML][HTML] Comprehensive geriatric assessment predicts radiation-induced acute toxicity in prostate cancer patients

K Paal, B Stranz, EM Thurner, U Langsenlehner… - Strahlentherapie und …, 2024 - Springer
Purpose The purpose of the present prospective study was to evaluate the significance of
geriatric conditions measured by a comprehensive geriatric assessment (GA) for the …

[HTML][HTML] A comprehensive study on non-cancer-related mortality risk factors in elderly gastric cancer patients post-curative surgery

Y Ushimaru, S Nagano, K Nishikawa, R Kawabata… - BMC …, 2024 - Springer
Background The increasing incidence of gastric cancer in the elderly underscores the need
for an in-depth understanding of the challenges and risks associated with surgical …

Assessing Frailty in Gastrointestinal Cancer: Two Diseases in One?

I Patel, A Winer - Current Oncology Reports, 2024 - Springer
Abstract Purposeof Review This review examines the challenges of treating gastrointestinal
cancer in the aging population, focusing on the importance of frailty assessment …

[HTML][HTML] Prediction of cognitive decline in older breast cancer survivors: the Thinking and Living with Cancer study

AP McDeed, K Van Dyk, X Zhou, W Zhai… - JNCI Cancer …, 2024 - academic.oup.com
Purpose Cancer survivors commonly report cognitive declines after cancer therapy. Due to
the complex etiology of cancer-related cognitive decline (CRCD), predicting who will be at …

Nutritional impairment, psychological health and quality of life among older adults with advanced cancer: A secondary analysis of a randomized clinical trial

S Singhal, Y Wang, Z Qin, DR Peterson… - Cancer …, 2024 - Wiley Online Library
Background Nutritional impairment is associated with treatment toxicity and worse overall
survival in patients with cancer. We aimed to (1) evaluate the association of nutritional …

[HTML][HTML] Updates on the Management of Colorectal Cancer in Older Adults

CDJ O'Donnell, J Hubbard, Z Jin - Cancers, 2024 - mdpi.com
Simple Summary The majority of cases of colorectal cancer occur in those over the age of
65. Treatment of colorectal cancer in older adults warrants specific considerations due to the …

[HTML][HTML] Pan-cancer analyses of the associations between 109 pre-existing conditions and cancer treatment patterns across 19 adult cancers

WH Chang, AG Lai - Scientific Reports, 2024 - nature.com
Comorbidities present considerable challenges to cancer treatment and care. However, little
is known about the effect of comorbidity on cancer treatment decisions across a wide range …

The FITNESS study: longitudinal geriatric assessment, treatment toxicity, and biospecimen collection to assess functional disability among older adults with lung …

M Grogan, R Hoyd, J Benedict, S Janse, N Williams… - Frontiers in …, 2024 - frontiersin.org
Introduction Older adults with chronic disease prioritize functional independence. We aimed
to describe the feasibility of capturing functional disability and treatment toxicity among older …