The association between gut microbiota and central nervous system (CNS) development
has garnered significant research attention in recent years. Evidence suggests bidirectional …

To date, Rett syndrome (RTT), a genetic disorder mainly caused by mutations in the X-linked
MECP2 gene, is increasingly considered a broad-spectrum pathology, instead of just a …

Rett syndrome (RTT) is a devastating neurodevelopmental disorder primarily caused by
mutations in the methyl-CpG binding protein 2 (Mecp2) gene. Here, we found that inhibition …

MECP2, CDKL5, and FMR1 are three X-linked neurodevelopmental genes associated with
Rett, CDKL5-, and fragile-X syndrome, respectively. These syndromes are characterized by …

Microglia are resident immune cells in the central nervous system (CNS) that play vital roles
in CNS development, homeostasis and disease pathogenesis. Genetic defects in microglia …

Williams syndrome (WS) is a genetic neurodevelopmental disorder caused by a
heterozygous microdeletion, characterized by hypersociability and unique neurocognitive …

Rett syndrome (RTT) is a rare neurodevelopmental disorder caused by mutation in the X-
linked gene methyl-CpG-binding protein 2 (Mecp2), a ubiquitously expressed transcriptional …

Rett syndrome is a rare genetic neurodevelopmental disease, affecting 1 in over 10 000
females born worldwide, caused by de novo mutations in the X-chromosome-located methyl …

Aspartame, an artificial sweetener, is consumed by millions of people globally. There are
multiple reports of aspartame and its metabolites affecting cognitive functions in animal …

Transducin β-like 1 X-linked receptor 1 (mouse Tbl1xr1) or TBL1X/Y related 1 (human
TBL1XR1), part of the NCoR/SMRT corepressor complex, is involved in nuclear receptor …