Immune checkpoint inhibitors associated cardiovascular immune-related adverse events

W Jo, T Won, A Daoud, D Čiháková - Frontiers in immunology, 2024 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are specialized monoclonal antibodies (mAbs) that
target immune checkpoints and their ligands, counteracting cancer cell-induced T-cell …

Exploring deep learning for carotid artery plaque segmentation: atherosclerosis to cardiovascular risk biomarkers

PK Jain, KV Tadepalli, S Roy, N Sharma - Multimedia Tools and …, 2024 - Springer
Atherosclerosis, caused by a variety of extrinsic risk factors, is the major cause of the
cardiovascular and cerebrovascular diseases that bring high mortality and morbidity …

Atherosclerotic plaque features relevant to rupture-risk detected by clinical photon-counting CT ex vivo: a proof-of-concept study

A Shami, J Sun, C Gialeli, H Markstad… - European Radiology …, 2024 - Springer
Background To identify subjects with rupture-prone atherosclerotic plaques before
thrombotic events occur is an unmet clinical need. Thus, this proof-of-concept study aims to …

Evaluating middle cerebral artery plaque characteristics and lenticulostriate artery morphology associated with subcortical infarctions at 7T MRI

X Bai, P Fan, Z Li, M Mossa‐Basha, Y Ju… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Lenticulostriate artery (LSA) obstruction is a potential cause of subcortical
infarcts. However, MRI LSA evaluation at 3T is challenging. Purpose To investigate middle …

Monoclonal antibodies for dyslipidemia in adults: a focus on vulnerable patients groups

NQ Wu, ZF Li, MY Lu, JJ Li - Expert Opinion on Biological Therapy, 2024 - Taylor & Francis
Introduction Dyslipidemia significantly contributes to atherosclerotic cardiovascular disease
(ASCVD). Patients with lipid-rich vulnerable plaques are particularly susceptible to …

Predictive value of the serum uric acid to high-density lipoprotein cholesterol ratio for culprit plaques in patients with acute coronary syndrome

F Deng, F Jia, Y Sun, L Zhang, J Han, D Li… - BMC Cardiovascular …, 2024 - Springer
Background Hyperuricemia and low level of high-density lipoprotein cholesterol (HDL-C)
are both risk factors for coronary artery disease (CAD). The uric acid to HDL-C ratio (UHR) …

Characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases

S Pan, D Xie, C Gao, K Xiong - Frontiers in Immunology, 2024 - frontiersin.org
The whole-body inflammatory response is evident in inflammatory diseases, where the
immune system secretes many related cytokines, leading to a powerful immune response …

Comparing various AI approaches to traditional quantitative assessment of the myocardial perfusion in [82Rb] PET for MACE prediction

S Bors, D Abler, M Dietz, V Andrearczyk, J Fageot… - Scientific Reports, 2024 - nature.com
Assessing the individual risk of Major Adverse Cardiac Events (MACE) is of major
importance as cardiovascular diseases remain the leading cause of death worldwide …

[HTML][HTML] Comparison of interventional treatment options for coronary calcified nodules: A sub-analysis of the ROTA. shock trial

F Blachutzik, S Meier, M Blachutzik, S Schlattner… - Cardiovascular …, 2024 - Elsevier
Background The optimal treatment for coronary calcified nodules (CNs) is still unclear. The
aim of this study was to compare the modification of these lesions by coronary intravascular …

[HTML][HTML] Value of carotid intima thickness in assessing advanced carotid plaque vulnerability: a study based on carotid artery ultrasonography and carotid plaque …

YC Zhao, J Zhang, F Wang, YM He, MJ Xu… - … Imaging in Medicine …, 2024 - ncbi.nlm.nih.gov
Background Research has shown that carotid intima-media thickness (CIMT) could help to
predict carotid plaque (CP) progression in patients with mild carotid stenosis. However, the …