[HTML][HTML] Fully bioresorbable hybrid opto-electronic neural implant system for simultaneous electrophysiological recording and optogenetic stimulation

M Cho, JK Han, J Suh, JJ Kim, JR Ryu, IS Min… - Nature …, 2024 - nature.com
Bioresorbable neural implants based on emerging classes of biodegradable materials offer
a promising solution to the challenges of secondary surgeries for removal of implanted …

A comprehensive review of optical fiber technologies in optogenetics and their prospective developments in future clinical therapies

S Chen, Z Wang, K Xiao, B He, J Zhao, X Yang… - Optics & Laser …, 2024 - Elsevier
As the incidence of neurological disorders rises, the need for innovative and minimally
invasive treatment methods is paramount. This review comprehensively explores the state …

Multimodal Technologies for Closed‐Loop Neural Modulation and Sensing

L Li, B Zhang, W Zhao, D Sheng, L Yin… - Advanced …, 2024 - Wiley Online Library
Existing methods for studying neural circuits and treating neurological disorders are typically
based on physical and chemical cues to manipulate and record neural activities. These …

[PDF][PDF] Localized APP expression results in progressive network dysfunction by disorganizing spike timing

SV da Silva, MG Haberl, K Gaur, R Patel, G Narayan… - Neuron, 2024 - cell.com
Progressive cognitive decline in Alzheimer's disease could either be caused by a spreading
molecular pathology or by an initially focal pathology that causes aberrant neuronal activity …

Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients

YM Wang, CW Liu, SY Chen, LY Lu, WC Liu… - Science Translational …, 2024 - science.org
Essential tremor (ET) is the most prevalent movement disorder, characterized primarily by
action tremor, an involuntary rhythmic movement with a specific frequency. However, the …

Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance

LF Jiang-Xie, A Drieu, K Bhasiin, D Quintero, I Smirnov… - Nature, 2024 - nature.com
The accumulation of metabolic waste is a leading cause of numerous neurological
disorders, yet we still have only limited knowledge of how the brain performs self-cleansing …

[HTML][HTML] BNST GABAergic neurons modulate wakefulness over sleep and anesthesia

M Li, W Li, S Liang, X Liao, M Gu, H Li, X Chen… - Communications …, 2024 - nature.com
The neural circuits underlying sleep-wakefulness and general anesthesia have not been
fully investigated. The GABAergic neurons in the bed nucleus of the stria terminalis (BNST) …

[HTML][HTML] An optrode array for spatiotemporally-precise large-scale optogenetic stimulation of deep cortical layers in non-human primates

AM Clark, A Ingold, CF Reiche, D Cundy III… - Communications …, 2024 - nature.com
Optogenetics has transformed studies of neural circuit function, but remains challenging to
apply to non-human primates (NHPs). A major challenge is delivering intense …

A System‐Level Feasibility Study of a Lead‐Free Ultrasonically Powered Light Delivery Implant for Optogenetics

S Baghaee Ivriq, K Laursen… - Advanced Intelligent …, 2024 - Wiley Online Library
Body implants play a crucial role in clinical applications, encompassing data acquisition,
diagnosis, and disease treatment. However, challenges in size, power consumption, and …

Fear learning: an evolving picture for plasticity at synaptic afferents to the amygdala

S Palchaudhuri, D Osypenko… - The …, 2024 - journals.sagepub.com
Unraveling the neuronal mechanisms of fear learning might allow neuroscientists to make
links between a learned behavior and the underlying plasticity at specific synaptic …