The protozoan parasite Plasmodium falciparum, responsible for the deadliest form of human
malaria, employs antigenic variation via monoallelic expression as a key survival strategy …

While often undetected and untreated, persistent seasonal asymptomatic malaria infections
remain a global public health problem. Despite the presence of parasites in the peripheral …

Apicomplexan parasites that reside within a parasitophorous vacuole harbor a conserved
pore-forming protein that enables small-molecule transfer across the parasitophorous …

The pathogenesis of severe Plasmodium falciparum malaria involves cytoadhesive
microvascular sequestration of infected erythrocytes, mediated by P. falciparum erythrocyte …

Cerebral malaria (CM), the most lethal complication of Plasmodium falciparum severe
malaria (SM), remains fatal for 15–25% of affected children despite the availability of …

Malaria remains a significant global health challenge, demanding a deeper understanding
of host immune responses for effective clearance of the parasitic infection. Cytokines, as …

While the malaria parasite Plasmodium falciparum has low average genome-wide diversity
levels, likely due to its recent introduction from a gorilla-infecting ancestor (approximately …

Strain-transcending antibodies against virulence-associated subsets of P. falciparum-
infected erythrocyte surface antigens could protect children from severe malaria. However …

Background The spleen plays a critical role in the immune response against malaria
parasite infection, where splenic fibroblasts (SFs) are abundantly present and contribute to …

Background Malaria has remained a major health concern for decades among people living
in tropical and sub-tropical countries. Plasmodium falciparum is one of the critical species …