Musculoskeletal (MSK) disorders significantly burden patients and society, resulting in high
healthcare costs and productivity loss. These disorders are the leading cause of physical …

Organoids are self-organized, three-dimensional structures derived from stem cells that can
mimic the structure and physiology of human organs. Patient-specific induced pluripotent …

Addressing large bone defects remains a significant challenge owing to the inherent
limitations in self‐healing capabilities, resulting in prolonged recovery and suboptimal …

Human organotypic bone models are an emerging technology that replicate bone
physiology and mechanobiology for comprehensive in vitro experimentation over prolonged …

Abstract Organ‐on‐a‐chip, also known as “tissue chip,” is an advanced platform based on
microfluidic systems for constructing miniature organ models in vitro. They can replicate the …

In the realm of studying joint-related diseases, there is a continuous quest for more accurate
and representative models. Recently, regenerative medicine and tissue engineering have …

Bone differentiation is crucial for skeletal development and maintenance. Its dysfunction can
cause various pathological conditions such as rickets, osteoporosis, osteogenesis …

Bone diseases such as osteoporosis and osteoarthritis have become important human
health problems, requiring a deeper understanding of the pathogenesis of related diseases …

The DNA excision repair protein ERCC1 and the DNA damage sensor protein, XPA are
highly overexpressed in patient samples of cisplatin‐resistant solid tumors including lung …

Platelet-rich plasma (PRP), a blood product containing high concentrations of platelets, has
been increasingly used for the treatment of a number of diseases because of its anti …