[HTML][HTML] Navigating the CRISPR/Cas Landscape for Enhanced Diagnosis and Treatment of Wilson's Disease
W Choi, S Cha, K Kim - Cells, 2024 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-
associated protein (Cas) system continues to evolve, thereby enabling more precise …
associated protein (Cas) system continues to evolve, thereby enabling more precise …
The type V effectors for CRISPR/Cas-mediated genome engineering in plants
R Zhang, N Chai, T Liu, Z Zheng, Q Lin, X Xie… - Biotechnology …, 2024 - Elsevier
A plethora of CRISPR effectors, such as Cas3, Cas9, and Cas12a, are commonly employed
as gene editing tools. Among these, Cas12 effectors developed based on Class II type V …
as gene editing tools. Among these, Cas12 effectors developed based on Class II type V …
Construction of Host Plant Insect‐Resistance Mutant Library by High‐Throughput CRISPR/Cas9 System and Identification of A Broad‐Spectrum Insect Resistance …
Insects pose significant challenges in cotton‐producing regions. Here, they describe a high‐
throughput CRISPR/Cas9‐mediated large‐scale mutagenesis library targeting endogenous …
throughput CRISPR/Cas9‐mediated large‐scale mutagenesis library targeting endogenous …
Precise fine-turning of GhTFL1 by base editing tools defines ideal cotton plant architecture
G Wang, F Wang, Z Xu, Y Wang, C Zhang, Y Zhou… - Genome Biology, 2024 - Springer
Background CRISPR/Cas-derived base editor enables precise editing of target sites and
has been widely used for basic research and crop genetic improvement. However, the …
has been widely used for basic research and crop genetic improvement. However, the …
An inducible CRISPR activation tool for accelerating plant regeneration
C Zhang, Y Tang, S Tang, L Chen, T Li, H Yuan… - Plant …, 2024 - cell.com
The inducible CRISPR activation (CRISPR-a) system offers unparalleled precision and
versatility for regulating endogenous genes, making it highly sought after in plant research …
versatility for regulating endogenous genes, making it highly sought after in plant research …
CRISPR/dCas13(Rx) Derived RNA N6‐methyladenosine (m6A) Dynamic Modification in Plant
L Yu, M Alariqi, B Li, A Hussain, H Zhou… - Advanced …, 2024 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) is the most prevalent internal modification of mRNA
and plays an important role in regulating plant growth. However, there is still a lack of …
and plays an important role in regulating plant growth. However, there is still a lack of …
Prime editing in plants: prospects and challenges
Prime editors are reverse transcriptase (RT)-based genome-editing tools that utilize double-
strand break (DSB)-free mechanisms to decrease off-target editing in genomes and …
strand break (DSB)-free mechanisms to decrease off-target editing in genomes and …
Application of an endogenous pGhαGloA promoter in CRISPR/Cas12a system for efficient genome editing to creat glandless cotton germplasm
C Li, Z Tuerxun, Y Yang, X Li, F Hui, J Li, Z Liu… - Journal of Integrative …, 2024 - Elsevier
The efficient genome editing tool (the CRISPR/Cas12a system) has been used in research
on plant functionional genomics and improvement of agronomic traits. In this study …
on plant functionional genomics and improvement of agronomic traits. In this study …
Genome editing based trait improvement in crops: current perspective, challenges and opportunities
The exponentially increasing population poses a serious threat to global food security.
Concurrently, the climate change condition also limits crop productivity by enhancing the …
Concurrently, the climate change condition also limits crop productivity by enhancing the …
Targeted genome editing for cotton improvement: prospects and challenges
Cotton is a highly profitable agricultural crop globally, valued for its valuable natural
cellulosic fibres, renewable biofuel potential, and rich edible oil content. Global cotton …
cellulosic fibres, renewable biofuel potential, and rich edible oil content. Global cotton …