Biofilms are organized bacterial communities embedded in an extracellular polymeric matrix
attached to living or abiotic surfaces. The development of biofilms is currently recognized as …

Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

Pathogenic fungi in the genus Candida can cause both superficial and serious systemic
disease, and are now recognized as major agents of hospital-acquired infection. Many …

Quorum sensing (QS) is one of the most studied cell-cell communication mechanisms in
fungi. Research in the last 20 years has explored various fungal QS systems that are …

Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …

Farnesol is a quorum-sensing molecule that inhibits filamentation in Candida albicans. Both
filamentation and quorum sensing are deemed to be important factors in C. albicans biofilm …

Fungal biofilms are an escalating clinical problem associated with significant rates of
mortality. Candida albicans is the most notorious of all fungal biofilm formers. However, non …

Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …

In recent years there has been an increasing appreciation that microbial biofilms are
ubiquitous, which has resulted in a number of studies on infectious diseases from a biofilm …

Candida albicans is the most prevalent human fungal pathogen, with an ability to inhabit
diverse host niches and cause disease in both immunocompetent and immunocompromised …