One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …

Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to
activated Protein C and an increased risk for venous thromboembolism. Deep venous …

Background The use of anticoagulant therapy during pregnancy is challenging because of
the potential for both fetal and maternal complications. This guideline focuses on the …

Growing evidence suggests that thrombophilia is associated with venous thromboembolism
(VTE) and adverse pregnancy outcomes. However, methodological limitations have made it …

Background Our aim was to assess the strength of the controversial association between
thrombophilia and fetal loss, and to examine whether it varies according to the timing or …

Recurrent miscarriage is a common pathology fond in 1% to 5% of reproductively active
couples. This chapter discusses the possible causes of recurrent miscarriage, and …

This article discusses the management of venous thromboembolism (VTE) and
thrombophilia, as well as the use of antithrombotic agents, during pregnancy and is part of …

This chapter about the use of antithrombotic agents during pregnancy is part of the Seventh
ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based …

Objective: To determine whether inherited and acquired thrombophilias are associated with
adverse obstetric complications. Study Design: A systematic review; studies where women …

The prospective evaluation of the effect of thromboprophylaxis in women with one
unexplained pregnancy loss from the 10th week of amenorrhea was performed. A total of …