Challenges and tissue engineering strategies of periodontal-guided tissue regeneration

Y Liu, L Guo, X Li, S Liu, J Du, J Xu, J Hu… - Tissue Engineering Part …, 2022 - liebertpub.com
Periodontitis is a chronic infectious oral disease with a high prevalence rate in the world,
and is a major cause of tooth loss. Nowadays, people have realized that the local …

[HTML][HTML] Role and application of stem cells in dental regeneration: A comprehensive overview

A Soudi, M Yazdanian, R Ranjbar, H Tebyanian… - Excli Journal, 2021 - ncbi.nlm.nih.gov
Recently, a growing attention has been observed toward potential advantages of stem cell
(SC)-based therapies in regenerative treatments. Mesenchymal stem/stromal cells (MSCs) …

Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration

JRJ Chew, SJ Chuah, KYW Teo, S Zhang, RC Lai… - Acta biomaterialia, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are potential therapeutics for the treatment of periodontal
defects. It is increasingly accepted that MSCs mediate tissue repair through secretion of …

Stem cell therapies for periodontal tissue regeneration: a network meta-analysis of preclinical studies

Q Li, G Yang, J Li, M Ding, N Zhou, H Dong… - Stem cell research & …, 2020 - Springer
Background Periodontal tissue regeneration (PTR) is the ultimate goal of periodontal
therapy. Currently, stem cell therapy is considered a promising strategy for achieving PTR …

Efficacy of stem cells on periodontal regeneration: systematic review of pre‐clinical studies

SA Tassi, NZ Sergio, MYO Misawa… - Journal of periodontal …, 2017 - Wiley Online Library
This systematic review aims to evaluate mesenchymal stem cells (MSC) periodontal
regenerative potential in animal models. MEDLINE, EMBASE and LILACS databases were …

Mesenchymal stem cells of dental origin for inducing tissue regeneration in periodontitis: a mini-review

B Hernández-Monjaraz, E Santiago-Osorio… - International journal of …, 2018 - mdpi.com
Periodontitis is a chronic disease that begins with a period of inflammation of the supporting
tissues of the teeth table and then progresses, destroying the tissues until loss of the teeth …

Periodontal ligament‐derived cells for periodontal regeneration in animal models: a systematic review

R Bright, K Hynes, S Gronthos… - Journal of periodontal …, 2015 - Wiley Online Library
Background and Objective Implantation of periodontal ligament stem cells is emerging as a
potential periodontal regenerative procedure. This systematic review considers the evidence …

Stem cell transplantation and cell-free treatment for periodontal regeneration

K Iwasaki, Y Peng, R Kanda, M Umeda… - International Journal of …, 2022 - mdpi.com
Increasing attention has been paid to cell-based medicines. Many in vivo and in vitro studies
have demonstrated the efficacy of stem cell transplantation for the regeneration of …

[HTML][HTML] Full physicochemical and biocompatibility characterization of a supercritical CO2 sterilized nano-hydroxyapatite/chitosan biodegradable scaffold for …

M Souto-Lopes, L Grenho, YA Manrique, MM Dias… - Biomaterials …, 2023 - Elsevier
Despite bone's innate self-renewal capability, some periodontal pathologic and traumatic
defects' size inhibits full spontaneous regeneration. This current research characterized a …

Periodontal wound healing and regeneration: Insights for engineering new therapeutic approaches

D Fraser, J Caton, DSW Benoit - Frontiers in Dental Medicine, 2022 - frontiersin.org
Periodontitis is a widespread inflammatory disease that leads to loss of the tooth supporting
periodontal tissues. The few therapies available to regenerate periodontal tissues have high …