Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine

J Nijs, SZ George, DJ Clauw… - The Lancet …, 2021 - thelancet.com
Chronic pain is a leading cause of disability globally and associated with enormous health-
care costs. The discrepancy between the extent of tissue damage and the magnitude of …

[HTML][HTML] Current concept of quantitative sensory testing and pressure pain threshold in neck/shoulder and low back pain

H Suzuki, S Tahara, M Mitsuda, H Izumi, S Ikeda… - Healthcare, 2022 - mdpi.com
In recent years, several published articles have shown that quantitative sensory testing
(QST) and pressure pain threshold (PPT) are useful in the analysis of neck/shoulder and low …

Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis

ME McPhee, HB Vaegter, T Graven-Nielsen - Pain, 2020 - journals.lww.com
Altered pronociceptive and antinociceptive mechanisms are often implicated in painful
conditions and have been increasingly studied over the past decade. For some painful …

[HTML][HTML] Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures

KA Sluka, TD Wager, SP Sutherland, PA Labosky… - Pain, 2023 - journals.lww.com
Chronic pain affects more than 50 million Americans. Treatments remain inadequate, in
large part, because the pathophysiological mechanisms underlying the development of …

The analgesic effect of transcranial direct current stimulation in fibromyalgia: a systematic review, meta-analysis, and meta-regression of potential influencers of …

PEP Teixeira, K Pacheco-Barrios, LC Branco… - … : Technology at the …, 2023 - Elsevier
Background There is tentative evidence to support the analgesic effect of transcranial direct
current stimulation (tDCS) in fibromyalgia (FM), with large variability in the effect size (ES) …

Haptics for human-computer interaction: From the skin to the brain

M Ziat - Foundations and Trends® in Human–Computer …, 2023 - nowpublishers.com
In recent years haptics has received considerable attention from the field of Human-
Computer Interactions (HCI) for its potential to provide more tangible and immersive …

[HTML][HTML] Effect of manual therapy with exercise in patients with chronic cervical radiculopathy: a randomized clinical trial

AM Alshami, DA Bamhair - Trials, 2021 - Springer
Background Research that has examined the effects of cervical spine mobilization on
hypoesthesia and hypersensitivity characteristics in patients with cervical radiculopathy is …

[HTML][HTML] Optimizing and accelerating the development of precision pain treatments for chronic pain: IMMPACT review and recommendations

RR Edwards, KL Schreiber, RH Dworkin, DC Turk… - The journal of pain, 2023 - Elsevier
Large variability in the individual response to even the most-efficacious pain treatments is
observed clinically, which has led to calls for a more personalized, tailored approach to …

Trigeminal and cervical sensitization during the four phases of the migraine cycle in patients with episodic migraine

S Di Antonio, M Castaldo, M Ponzano… - … : The Journal of …, 2022 - Wiley Online Library
Objective Assessing mechanical pain thresholds from trigeminal, cervical, and distal pain‐
free areas during the four phases of a migraine cycle in patients with episodic migraine …

Is preoperative quantitative sensory testing related to persistent postsurgical pain? A systematic literature review

N van Helmond, HM Aarts, H Timmerman… - Anesthesia & …, 2020 - journals.lww.com
Persistent postsurgical pain (PPSP) is a common complication of surgery that significantly
affects quality of life. A better understanding of which patients are likely to develop PPSP …