Medullary thyroid carcinoma beyond surgery: advances, challenges, and perspectives

L Ceolin, MA da Silveira Duval… - Endocrine-related …, 2019 - erc.bioscientifica.com
Medullary thyroid carcinoma (MTC) is a rare type of tumor that originates from thyroid C cells
and accounts for 2–4% of all malignant thyroid neoplasms. MTC may occur sporadically or …

Molecular alterations in thyroid cancer: from bench to clinical practice

E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …

The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults

KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Evaluation of gender inequity in thyroid cancer diagnosis: differences by sex in US thyroid cancer incidence compared with a meta-analysis of subclinical thyroid …

K LeClair, KJL Bell, L Furuya-Kanamori… - JAMA internal …, 2021 - jamanetwork.com
Importance Thyroid cancer is more common in women than in men, but the associated
causes of these differences are not fully understood. Objective To compare sex-specific …

An improved deep learning approach for detection of thyroid papillary cancer in ultrasound images

H Li, J Weng, Y Shi, W Gu, Y Mao, Y Wang, W Liu… - Scientific reports, 2018 - nature.com
Unlike daily routine images, ultrasound images are usually monochrome and low-resolution.
In ultrasound images, the cancer regions are usually blurred, vague margin and irregular in …

Clinical utility of 177Lu‐DOTATATE PRRT in somatostatin receptor‐positive metastatic medullary carcinoma of thyroid patients with assessment of efficacy, survival …

RV Parghane, C Naik, S Talole, A Desmukh… - Head & …, 2020 - Wiley Online Library
Background The primary aim of this study was to evaluate the therapeutic efficacy and
outcome of 177Lu‐DOTATATE peptide receptor radionuclide therapy (PRRT) in …

Sporadic medullary thyroid carcinoma: towards a precision medicine

A Matrone, C Gambale, A Prete, R Elisei - Frontiers in endocrinology, 2022 - frontiersin.org
Medullary thyroid carcinoma (MTC) is a neuroendocrine malignant tumor originating from
parafollicular C-cells producing calcitonin. Most of cases (75%) are sporadic while the …

Real-world efficacy and safety of cabozantinib and vandetanib in advanced medullary thyroid cancer

VF Koehler, P Adam, K Frank-Raue, F Raue, E Berg… - Thyroid, 2021 - liebertpub.com
Background: Management of patients with advanced medullary thyroid cancer (MTC)
remains a therapeutic challenge. The multi-tyrosine kinase inhibitors (TKIs) vandetanib and …

Other markers of medullary thyroid cancer, not only calcitonin

S Censi, J Manso, C Mian - European Journal of Endocrinology, 2023 - academic.oup.com
Background Medullary thyroid cancer (MTC) is a rare neuroendocrine tumor originating from
parafollicular C-cells. It represents 2% of all thyroid malignancies and 0.4-1.4% of all thyroid …

Prognostic impact of inflammatory markers PLR, LMR, PDW, MPV in medullary thyroid carcinoma

C Li, H Zhang, S Li, D Zhang, J Li, G Dionigi… - Frontiers in …, 2022 - frontiersin.org
Background Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR),
lymphocyte-to-monocyte ratio (LMR), mean platelet volume (MPV), and platelet distribution …