Sarcoidosis and COVID-19: at the cross-road between immunopathology and clinical manifestation
Coronavirus disease 2019 (COVID-19) has been associated with dysregulation of the
immune system featuring inappropriate immune responses, exacerbation of inflammatory …
immune system featuring inappropriate immune responses, exacerbation of inflammatory …
An inflammatory triangle in Sarcoidosis: PPAR-γ, immune microenvironment, and inflammation
Introduction Sarcoidosis is an inflammatory disorder characterized by granuloma formation
in several organs. Sarcoidosis patients experience higher inflammatory responses resulting …
in several organs. Sarcoidosis patients experience higher inflammatory responses resulting …
Elevated serum amyloid A levels are not specific for sarcoidosis but associate with a fibrotic pulmonary phenotype
E Beijer, C Roodenburg-Benschop… - Cells, 2021 - mdpi.com
Elevated Serum Amyloid A (SAA) levels have been found in several inflammatory diseases,
including sarcoidosis. SAA is suggested to be involved in sarcoidosis pathogenesis by …
including sarcoidosis. SAA is suggested to be involved in sarcoidosis pathogenesis by …
Pentraxin 3 inhibits complement-driven macrophage activation to restrain granuloma formation in sarcoidosis
Rationale: Sarcoidosis is a multisystemic inflammatory disease characterized by the
formation of granulomas in response to persistent stimuli. The long pentraxin PTX3 …
formation of granulomas in response to persistent stimuli. The long pentraxin PTX3 …
[HTML][HTML] Sarcoidosis: Progression to the chronic stage and pathogenic based treatment (narrative review)
A Malkova, Y Zinchenko, A Starshinova… - Frontiers in …, 2022 - frontiersin.org
Many factors confirm the autoimmune nature of sarcoidosis and help in determining the
strategy of patient management and treatment initiation. However, the causes and the …
strategy of patient management and treatment initiation. However, the causes and the …
Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis
R Kraaijvanger, M Janssen Bonás, JC Grutters… - Respiratory …, 2024 - Springer
Background Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily
affecting the lungs. Treatment is needed when disease symptoms worsen and organ …
affecting the lungs. Treatment is needed when disease symptoms worsen and organ …
[HTML][HTML] BATF2 and PDK4 as diagnostic molecular markers of sarcoidosis and their relationship with immune infiltration
J He, X Li, J Zhou, R Hu - Annals of Translational Medicine, 2022 - ncbi.nlm.nih.gov
Background Sarcoidosis (SA) is an immune disorder disease featuring granulomas
formation with a controversial etiopathogenesis. We aimed to uncover potential markers for …
formation with a controversial etiopathogenesis. We aimed to uncover potential markers for …
Anti-inflammatory properties of the alpha-melanocyte-stimulating hormone in models of granulomatous inflammation
AH Shahraki, R Tian, C Zhang, NL Fregien, P Bejarano… - Lung, 2022 - Springer
Purpose Alpha-melanocyte stimulating hormone (α-MSH) is known to have anti-
inflammatory effects. However, the anti-inflammatory properties of α-MSH on normal …
inflammatory effects. However, the anti-inflammatory properties of α-MSH on normal …
The M2a Macrophage Phenotype Accompanies Pulmonary Granuloma Resolution in Mmp12 Knock-Out Mice Instilled with Multiwall Carbon Nanotubes
D Ogburn, S Bhalla, N Leffler, A Mohan… - International journal of …, 2021 - mdpi.com
Sarcoidosis is a chronic disease with unknown etiology and pathophysiology, characterized
by granuloma formation. Matrix Metalloproteinase-12 (MMP12) is an elastase implicated in …
by granuloma formation. Matrix Metalloproteinase-12 (MMP12) is an elastase implicated in …
Innate and adaptive immunity in noninfectious granulomatous lung disease
AS McKee, SM Atif, MT Falta… - The Journal of …, 2022 - journals.aai.org
Sarcoidosis and chronic beryllium disease are noninfectious lung diseases that are
characterized by the presence of noncaseating granulomatous inflammation. Chronic …
characterized by the presence of noncaseating granulomatous inflammation. Chronic …