RISING STARS: Mechanistic insights into maternal–fetal cross talk and islet beta-cell development

S Jo, EU Alejandro - Journal of Endocrinology, 2023 - joe.bioscientifica.com
The metabolic health trajectory of an individual is shaped as early as prepregnancy, during
pregnancy, and lactation period. Both maternal nutrition and metabolic health status are …

Palmitate induces integrated stress response and lipoapoptosis in trophoblasts

PK Sahoo, C Krishnamoorthy, JR Wood… - Cell Death & …, 2024 - nature.com
Maternal obesity increases the risk of childhood obesity and programs the offspring to
develop metabolic syndrome later in their life. Palmitate is the predominant saturated free …

Lipid aldehydes 4-hydroxynonenal and 4-hydroxyhexenal exposure differentially impact lipogenic pathways in human placenta

A Rasool, T Mahmoud, P O'Tierney-Ginn - Biology, 2023 - mdpi.com
Simple Summary Omega-3 fatty acids are vital for optimal fetal and placental development.
Under conditions of oxidative stress, toxic by-products called lipid aldehydes are produced …

Effects of a High-Fat Diet and Docosahexaenoic Acid during Pregnancy on Fatty Acid Composition in the Fetal Livers of Mice

D Álvarez, M Ortiz, G Valdebenito, N Crisosto… - Nutrients, 2023 - mdpi.com
A high-fat diet (HFD) during pregnancy promotes fat accumulation and reduces
docosahexaenoic acid (DHA) levels in the liver of the offspring at postnatal ages, which can …

Obesity during Pregnancy in the Horse: Effect on Term Placental Structure and Gene Expression, as Well as Colostrum and Milk Fatty Acid Concentration

M Robles, D Rousseau-Ralliard, C Dubois, T Josse… - Veterinary …, 2023 - mdpi.com
Simple Summary The prevalence of obesity in horses is high, but the impact of obesity
during pregnancy on placental function and milk production is currently unknown in this …

[HTML][HTML] Placental Fatty Acid Metabolism and Transport in a Rat Model of Gestational Diabetes Mellitus

JS Mishra, S Kumar - Journal of women's health and development, 2023 - ncbi.nlm.nih.gov
Placental Fatty Acid Metabolism and Transport in a Rat Model of Gestational Diabetes Mellitus -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Association between maternal obesity, essential fatty acids and biomarkers of fetal liver function

M Ortiz, F Sánchez, D Álvarez, C Flores… - … and Essential Fatty …, 2023 - Elsevier
Maternal obesity and the imbalance in linoleic acid (C18: 2 n-6, LA) and alpha-linolenic acid
(C18: 3 n-3, ALA) levels are related with hepatic disturbances in the offspring. However …

Free Fatty Acid-Induced Cellular Stress Response and Protective Role of Palmitoleate

PK Sahoo - 2023 - search.proquest.com
Maternal obesity has emerged as a significant health challenge in the 21 st century and has
been shown to influence the health of the fetus in utero and later in life. The prevalence of …

Placental inflammation, oxidative stress, and fetal outcomes in maternal obesity

CXW Zhang, AA Candia, AN Sferruzzi-Perri - Trends in Endocrinology & …, 2024 - cell.com
The obesity epidemic has led to a growing body of research investigating the consequences
of maternal obesity on pregnancy and offspring health. The placenta, traditionally viewed as …