4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE)
have changed significantly since the Duke Criteria were published in 1994 and modified in …

Compared with the extensive data on left‐sided infective endocarditis (IE), there is much
less published information on the features and management of right‐sided IE. Right‐sided …

A thrombin-like serine protease, jararassin-I, was isolated from the venom of Bothrops
jararaca. The protein was obtained in high yield and purity by a single chromatographic step …

With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in
cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with …

Cardiac implantable electronic device (CIED) infection is a potentially devastating
complication of CIED procedures, causing significant morbidity and mortality for patients. Of …

Pacemaker-related infections remain a constant concern due to increased risk of patient
morbidity and mortality. Although transvenous pacemakers are expected to have an …

Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …

Importance Complete hardware removal is a class I recommendation for cardiovascular
implantable electronic device (CIED) infection, but practice patterns and outcomes remain …