Women are about twice as likely as are men to develop depression during their lifetime. This
Series paper summarises evidence regarding the epidemiology on gender differences in …

Psychology has historically been concerned, first and foremost, with explaining the causal
mechanisms that give rise to behavior. Randomized, tightly controlled experiments are …

Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

Disorders of the brain can exhibit considerable epidemiological comorbidity and often share
symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing …

Neuroticism is an important risk factor for psychiatric traits, including depression, anxiety,,
and schizophrenia,–. At the time of analysis, previous genome-wide association studies …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

We introduce multi-trait analysis of GWAS (MTAG), a method for joint analysis of summary
statistics from genome-wide association studies (GWAS) of different traits, possibly from …

Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

INTRODUCTION Brain disorders may exhibit shared symptoms and substantial
epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed …

In this target article, we argue that personality processes, personality structure, and
personality development have to be understood and investigated in integrated ways in order …