[HTML][HTML] Biphalin—A Potent Opioid Agonist—As a Panacea for Opioid System-Dependent Pathophysiological Diseases?

P Redkiewicz, J Dyniewicz, A Misicka - International Journal of Molecular …, 2021 - mdpi.com
Biphalin, one of the opioid agonists, is a dimeric analog of enkephalin with a high affinity for
opioid receptors. Opioid receptors are widespread in the central nervous system and in …

Biomedical Potential of Keratin-Biphalin Wound Dressing in Diabetic Mice: In Vitro and In Vivo Studies

M Rybka, Ł Mazurek, J Czuwara… - Journal of Natural …, 2024 - Taylor & Francis
Strategies for successful healing of diabetic wounds are lacking. Natural-derived dressings
have gained much attention due to their promising properties. We hypothesized that keratin …

The analgesic hybrid of dermorphin/substance P and analog of enkephalin improve wound healing in streptozotocin‐induced diabetic rats

A Muchowska, P Redkiewicz, K Różycki… - Wound Repair and …, 2020 - Wiley Online Library
The purpose of this study was to investigate the effect of the peptide analgesic hybrid
compounds: AWL3106 analog of dermorphin and substance P (7‐11), and biphalin …

The influence of a synthetic growth hormone‐releasing hormone analogue G11 and opioid peptide biphalin on selected fibroblasts parameters relevant to wound …

P Redkiewicz, J Dyniewicz, E Witkowska… - Journal of Peptide …, 2023 - Wiley Online Library
The treatment of hard‐to‐heal chronic wounds is still a major medical problem and an
economic and social burden. In this work, we examine the proregenerative potential of two …