Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Recent progress of targeted G-quadruplex-preferred ligands toward cancer therapy

S Asamitsu, S Obata, Z Yu, T Bando, H Sugiyama - Molecules, 2019 - mdpi.com
A G-quadruplex (G4) is a well-known nucleic acid secondary structure comprising guanine-
rich sequences, and has profound implications for various pharmacological and biological …

New horizons for diagnostics and therapeutic applications of graphene and graphene oxide

L Feng, L Wu, X Qu - Advanced Materials, 2013 - Wiley Online Library
Graphene, a one‐atom‐thick two‐dimensional (2D) layer of sp2‐bonded carbon, has
received worldwide attention owing to its extraordinary physical and chemical properties …

Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs

Q Cao, Y Li, E Freisinger, PZ Qin, RKO Sigel… - Inorganic Chemistry …, 2017 - pubs.rsc.org
Although cisplatin and its analogues have been widely utilized as anticancer metallodrugs
in clinics, their serious side effects and damage to normal tissues cannot be avoided …

The promise of self-assembled 3D supramolecular coordination complexes for biomedical applications

A Casini, B Woods, M Wenzel - Inorganic Chemistry, 2017 - ACS Publications
In the supramolecular chemistry field, coordination-driven self-assembly has provided the
basis for tremendous growth across many subdisciplines, spanning from fundamental …

Interaction of metal complexes with G‐quadruplex DNA

SN Georgiades, NH Abd Karim… - Angewandte Chemie …, 2010 - Wiley Online Library
Guanine‐rich sequences of DNA can assemble into tetrastranded structures known as G‐
quadruplexes. It has been suggested that these secondary DNA structures could be …

Ligand design to acquire specificity to intended G‐quadruplex structures

S Asamitsu, T Bando… - Chemistry–A European …, 2019 - Wiley Online Library
AG‐quadruplex is a nucleic acid secondary structure that is adopted by guanine‐rich
sequences, and is considered to be relevant in various pharmacological and biological …

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

Y Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
Telomeres are present at the ends of all eukaryotic chromosomes. Human telomeres play an
important role in critical processes underlying genome stability, cancer, and aging, and their …

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

M Mangino, SJ Hwang, TD Spector… - Human molecular …, 2012 - academic.oup.com
Leukocyte telomere length (LTL) is associated with a number of common age-related
diseases and is a heritable trait. Previous genome-wide association studies (GWASs) …