Engineered biomaterials for in situ tissue regeneration
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …
Bone repair biomaterials: a perspective from immunomodulation
Y Wang, H Zhang, Y Hu, Y Jing… - Advanced Functional …, 2022 - Wiley Online Library
With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …
Biomimetic glycopeptide hydrogel coated PCL/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo …
The reconstruction of large cranial bone defects by bioactive materials without exogenous
cells or growth factors remains a substantial clinical challenge. Here, synthetic fibrous …
cells or growth factors remains a substantial clinical challenge. Here, synthetic fibrous …
Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
The multifaceted roles of macrophages in bone regeneration: a story of polarization, activation and time
C Schlundt, H Fischer, CH Bucher, C Rendenbach… - Acta biomaterialia, 2021 - Elsevier
To present knowledge, macrophages are found in all tissues of the human body. They are a
cell population with high plasticity which come with a multitude of functions which appear to …
cell population with high plasticity which come with a multitude of functions which appear to …
Biomaterials: foreign bodies or tuners for the immune response?
E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
Mesenchymal stem cell-macrophage crosstalk and bone healing
Recent research has brought about a clear understanding that successful fracture healing is
based on carefully coordinated cross-talk between inflammatory and bone forming cells. In …
based on carefully coordinated cross-talk between inflammatory and bone forming cells. In …
Current advances in immunomodulatory biomaterials for bone regeneration
Biomaterials with suitable surface modification strategies are contributing significantly to the
rapid development of the field of bone tissue engineering. Despite these encouraging …
rapid development of the field of bone tissue engineering. Despite these encouraging …
Inflammation, fracture and bone repair
The reconstitution of lost bone is a subject that is germane to many orthopedic conditions
including fractures and non-unions, infection, inflammatory arthritis, osteoporosis …
including fractures and non-unions, infection, inflammatory arthritis, osteoporosis …
A biomimetic hierarchical nanointerface orchestrates macrophage polarization and mesenchymal stem cell recruitment to promote endogenous bone regeneration
SS Jin, DQ He, D Luo, Y Wang, M Yu, B Guan, Y Fu… - ACS …, 2019 - ACS Publications
The host immune response to bone biomaterials is vital in determining scaffold fates and
bone regeneration outcomes. The nanometer-scale interface of biomaterials, which …
bone regeneration outcomes. The nanometer-scale interface of biomaterials, which …