Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Although fungal infections contribute substantially to human morbidity and mortality, the
impact of these diseases on human health is not widely appreciated. Moreover, despite the …

Abstract Problem/Condition: Candidemia is a bloodstream infection (BSI) caused by yeasts
in the genus Candida. Candidemia is one of the most common health care–associated BSIs …

Only five species account for 92% of cases of candidemia (C andida albicans, C. glabrata,
C. tropicalis, C. parapsilosis, and C. krusei); however, their distribution varies in population …

Objectives Candidaemia is a serious hazard to hospitalized patients, but European
epidemiological data are restricted to national studies focusing on Northern Europe …

The incidence of infections caused by Candida species (candidosis) has increased
considerably over the past three decades, mainly due to the rise of the AIDS epidemic, an …

Assessment of the global burden and epidemiologic trends of fungal diseases is critical to
prioritizing prevention strategies, diagnostic modalities, and therapeutic interventions. The …

Neutrophils are the first line of defense at the site of an infection. They encounter and kill
microbes intracellularly upon phagocytosis or extracellularly by degranulation of …

Abstract Background. Invasive fungal infections (IFIs) are a major cause of morbidity and
mortality among organ transplant recipients. Multicenter prospective surveillance data to …

Health care-associated infections (HAIs) have become more common as medical care has
grown more complex and patients have become more complicated. HAIs are associated …