Plant tissue culture environment as a switch-key of (epi) genetic changes
PT Bednarek, R Orłowska - Plant Cell, Tissue and Organ Culture (PCTOC), 2020 - Springer
The in vitro tissue cultures are, beyond all difficulties, an essential tool in basic research as
well as in commercial applications. Numerous works devoted to plant tissue cultures proved …
well as in commercial applications. Numerous works devoted to plant tissue cultures proved …
Dynamic expression of DNA methyltransferases (DNMTs) in oocytes and early embryos
F Uysal, G Akkoyunlu, S Ozturk - Biochimie, 2015 - Elsevier
Epigenetic mechanisms play critical roles in oogenesis and early embryo development in
mammals. One of these epigenetic mechanisms, DNA methylation is accomplished through …
mammals. One of these epigenetic mechanisms, DNA methylation is accomplished through …
Environmental chemical exposures and human epigenetics
L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …
approximately 24% of diseases are caused by environmental exposures that might be …
Melatonin enhances mitochondrial biogenesis and protects against rotenone‐induced mitochondrial deficiency in early porcine embryos
YJ Niu, W Zhou, ZW Nie, KT Shin… - Journal of pineal …, 2020 - Wiley Online Library
Melatonin, a major hormone of the pineal gland, exerts many beneficial effects on
mitochondria. Several studies have shown that melatonin can protect against toxin‐induced …
mitochondria. Several studies have shown that melatonin can protect against toxin‐induced …
An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming
MAMM Ferraz, HS Rho, D Hemerich… - Nature …, 2018 - nature.com
Worldwide over 5 million children have been conceived using assisted reproductive
technology, and research has concentrated on increasing the likelihood of ongoing …
technology, and research has concentrated on increasing the likelihood of ongoing …
DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids
The number of children born since the origin of Assisted Reproductive Technologies (ART)
exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been …
exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been …
Extracellular vesicles and the oviduct function
EA Harris, KK Stephens, W Winuthayanon - International Journal of …, 2020 - mdpi.com
In mammals, the oviduct (or the Fallopian tube in humans) can be divided into the
infundibulum (responsible for oocyte pick-up), ampulla (site of fertilization), isthmus (where …
infundibulum (responsible for oocyte pick-up), ampulla (site of fertilization), isthmus (where …
DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes
Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …
Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes
B Petersen, A Frenzel, A Lucas‐Hahn… - …, 2016 - Wiley Online Library
Background Xenotransplantation is considered to be a promising solution to the growing
demand for suitable donor organs for transplantation. Despite tremendous progress in the …
demand for suitable donor organs for transplantation. Despite tremendous progress in the …
Epigenetic reprogramming during spermatogenesis and male factor infertility
HM McSwiggin, AM O'doherty - Reproduction, 2018 - rep.bioscientifica.com
Infertility is an often devastating diagnosis encountered by around one in six couples who
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …