Traditional antibiotic dosing was not designed for today's escalating antibiotic resistance,
lack of novel antibiotics and growing complexity in patient populations. Dosing that ensures …

Cystic fibrosis affects several organs, predisposing patients to severe bacterial respiratory
infections, including those caused by methicillin-resistant Staphylococcus aureus. Cystic …

Highlights•Bronchoalveolar lavage for determining epithelial lining fluid exposures of
antibiotics.•Discussion about conducting intrapulmonary pharmacokinetic studies in critically …

Abstract Staphylococcus aureus (S. aureus), including methicillin-resistant S. aureus
(MRSA), is an important aetiological cause of community-acquired pneumonia (CAP) and …

Nosocomial infections or healthcare-acquired infections are a common cause of increased
morbidity and mortality among hospitalized patients. Cancer patients are at an increased …

Background The increasing prevalence of ventilator-associated pneumonia (VAP) due to
either multidrug-resistant (MDR) organisms or infections with limited treatment options (ie …

There has been a resurgence of interest in aerosolization of antibiotics for treatment of
patients with severe pneumonia caused by multidrug-resistant pathogens. A combination …

Objectives To achieve the therapeutic effects, antibiotics must penetrate rapidly into infection
sites and bind to targets. This study reviewed updated knowledge on the ability of antibiotics …

Objectives Despite recent advances, antibiotic therapy of ventilator-associated pneumonia
(VAP) in ICU patients is still challenging. We assessed the impact of imipenem and amikacin …

Pneumonia komunitas merupakan penyakit infeksi pada parenkim paru-paru yang
mengancam jiwa sehingga dapat diberikan terapi antibiotik empiris. Penelitian ini bertujuan …