Microbial colonization from the fetus to early childhood—a comprehensive review

V Senn, D Bassler, R Choudhury… - Frontiers in cellular …, 2020 - frontiersin.org
The development of the neonatal gastrointestinal tract microbiota remains a poorly
understood process. The interplay between neonatal (gestational age, genetic background) …

Non-invasive prenatal testing using fetal DNA

G Breveglieri, E D'Aversa, A Finotti… - Molecular diagnosis & …, 2019 - Springer
Non-invasive prenatal diagnosis (NIPD) is based on fetal DNA analysis starting from a
simple peripheral blood sample, thus avoiding risks associated with conventional invasive …

Presence of fetal DNA in maternal plasma and serum

YMD Lo, N Corbetta, PF Chamberlain, V Rai… - The lancet, 1997 - thelancet.com
Background The potential use of plasma and serum for molecular diagnosis has generated
interest. Tumour DNA has been found in the plasma and serum of cancer patients, and …

Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum.

DW Bianchi, GK Zickwolf, GJ Weil… - Proceedings of the …, 1996 - National Acad Sciences
Rare nucleated fetal cells circulate within maternal blood. Noninvasive prenatal diagnosis
by isolation and genetic analysis of these cells is currently being undertaken. We sought to …

Non-invasive fetal genetic screening by digital analysis

S Quake, HMC Fan - US Patent 7,888,017, 2011 - Google Patents
The present methods are exemplified by a process in which maternal blood containing fetal
DNA is diluted to a nominal value of approximately 0.5 genome equivalent of DNA per …

Non-invasive prenatal diagnosis

YMD Lo, JS Wainscoat - US Patent 6,258,540, 2001 - Google Patents
The invention relates to a detection method performed on a maternal serum or plasma
sample from a pregnant female, which method comprises detecting the presence of a …

Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure

SC Strom, RA Fisher, MT Thompson, AJ Sanyal… - …, 1997 - journals.lww.com
The limited donor organ supply has led to several bridging techniques to sustain patients
with acute and subacute liver failure. We report here the prospective, controlled trial of …

Methods for detection of genetic disorders

RS Dhallan - US Patent 7,727,720, 2010 - Google Patents
First worldwide family litigation filed litigation https://patents. darts-ip. com/? family=
46322521&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Noninvasive diagnosis of fetal aneuploidy by sequencing

HMC Fan, SR Quake - US Patent 8,195,415, 2012 - Google Patents
Disclosed is a method to achieve digital quantification of DNA (ie, counting differences
between identical sequences) using direct shotgun sequencing followed by mapping to the …

Methods for detection of genetic disorders

RS Dhallan - US Patent 7,332,277, 2008 - Google Patents
First worldwide family litigation filed litigation https://patents. darts-ip. com/? family=
35375636&utm_source= google_patent&utm_medium= platform_link&utm_campaign …