Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

Answer questions and earn CME/CNE Comorbidity is common among cancer patients and,
with an aging population, is becoming more so. Comorbidity potentially affects the …

Population ageing has substantially contributed to the rising number of new cancer cases
worldwide. We document cancer incidence patterns in 2012 among older adults globally …

Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …

OBJECTIVE To identify barriers and solutions for the recruitment and retention of older
(aged≥ 65 years) people in clinical trials. DESIGN Systematic literature review. METHODS …

Immune checkpoint inhibitors, including those targeting the programmed cell death
1/programmed cell death ligand 1 and cytotoxic T lymphocyte antigen 4 pathways, are …

Recent reports have highlighted the distinct roles and occasional tension between
randomised controlled trials (RCTs) and population-based observational research (Concato …

Importance Seminal investigation 2 decades ago alerted the oncology community to age
disparities in participation in cooperative group trials; less is known about whether these …

Importance Substantial progress has been made in cancer diagnosis and treatment,
resulting in a steady improvement in cancer survival. The degree of improvement by age …

Breast cancer is a heterogeneous disease, with different subtypes having a distinct
biological, molecular, and clinical course. Assessments of standard clinical and pathological …