[HTML][HTML] Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment

D Li, H Chen, H Liu, D Schlenk, J Mu, S Lacorte… - Environment …, 2021 - Elsevier
Anticancer drugs are a group of therapeutic agents used to enhance cell death in targeted
cell types of neoplasia. Because of frequent use and eventual discharge, they have been …

Population‐level consequences for wild fish exposed to sublethal concentrations of chemicals–a critical review

PB Hamilton, IG Cowx, MF Oleksiak… - Fish and …, 2016 - Wiley Online Library
Concentrated chemical spills have been shown to impact adversely on fish populations and
even cause localized population extinctions. Evaluating population‐level impacts of …

Anticancer drugs in surface waters: what can we say about the occurrence and environmental significance of cytotoxic, cytostatic and endocrine therapy drugs?

JP Besse, JF Latour, J Garric - Environment international, 2012 - Elsevier
This study considers the implications and research needs arising from anticancer (also
referred to as antineoplastic) drugs being released into the aquatic environment, for the …

Incidence of anticancer drugs in an aquatic urban system: from hospital effluents through urban wastewater to natural environment

L Ferrando-Climent, S Rodriguez-Mozaz… - Environmental Pollution, 2014 - Elsevier
The presence of 10 anticancer drugs was studied along the entire urban water cycle-from
hospital effluents through urban wastewater treatment plant till surface waters-and their …

The read-across hypothesis and environmental risk assessment of pharmaceuticals

M Rand-Weaver, L Margiotta-Casaluci… - … science & technology, 2013 - ACS Publications
Pharmaceuticals in the environment have received increased attention over the past
decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low …

Highly active human pharmaceuticals in aquatic systems: a concept for their identification based on their mode of action

V Christen, S Hickmann, B Rechenberg, K Fent - Aquatic toxicology, 2010 - Elsevier
Widespread occurrence of traces of pharmaceuticals (ng/L to μg/L) has been reported in
aquatic systems. However, their effects on the environment and their environmental risks …

Cytostatic drugs and metabolites in municipal and hospital wastewaters in Spain: filtration, occurrence, and environmental risk

N Negreira, ML de Alda, D Barceló - Science of the total environment, 2014 - Elsevier
Concerns about cytostatic anticancer drugs in the environment are increasing, mainly due to
the lack of knowledge about the fate and impact of these cytotoxic compounds in the water …

Pharmaceuticals and personal care products: A critical review of the impacts on fish reproduction

MD Overturf, JC Anderson, Z Pandelides… - Critical reviews in …, 2015 - Taylor & Francis
Research in environmental toxicology involving pharmaceuticals and personal care
products (PPCPs) has increased greatly over the last 10–15 years. Much research has been …

Pharmaceuticals in the aquatic environment: steroids and anti-steroids as high priorities for research

TJ Runnalls, L Margiotta-Casaluci… - … and Ecological Risk …, 2010 - Taylor & Francis
Many human pharmaceuticals, with many modes of action, are present in the aquatic
environment. It is very difficult to know which of these might pose a threat to aquatic …

Molecular biomarkers of endocrine disruption in small model fish

S Scholz, I Mayer - Molecular and Cellular Endocrinology, 2008 - Elsevier
A wide range of environmental contaminants can interfere with hormonal regulation in
vertebrates. These endocrine disrupting chemicals (EDCs) are of high relevance for human …