A review of the microbial production of bioactive natural products and biologics
JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …
also known as natural products. Natural products have been a prolific source and an …
Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects
AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half
of the world population is still exposed to the risk of contracting malaria. Developing an …
of the world population is still exposed to the risk of contracting malaria. Developing an …
Malaria rapid diagnostic tests: challenges and prospects
JC Mouatcho, JPD Goldring - Journal of medical …, 2013 - microbiologyresearch.org
In the last decade, there has been an upsurge of interest in developing malaria rapid
diagnostic test (RDT) kits for the detection of Plasmodium species. Three antigens …
diagnostic test (RDT) kits for the detection of Plasmodium species. Three antigens …
Challenges and strategies for developing efficacious and long-lasting malaria vaccines
Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …
challenges remain for achieving highly efficacious and durable vaccines against …
Comprehensive review on various strategies for antimalarial drug discovery
M Mishra, VK Mishra, V Kashaw, AK Iyer… - European journal of …, 2017 - Elsevier
The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …
limiting our ability to manage this severe disease and finally lead to a massive global health …
A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children
SB Sirima, B Mordmüller, P Milligan, UA Ngoa… - Vaccine, 2016 - Elsevier
Background GMZ2 is a recombinant protein malaria vaccine, comprising two blood-stage
antigens of Plasmodium falciparum, glutamate-rich protein and merozoite surface protein 3 …
antigens of Plasmodium falciparum, glutamate-rich protein and merozoite surface protein 3 …
[HTML][HTML] Recent advances in recombinant protein-based malaria vaccines
SJ Draper, E Angov, T Horii, LH Miller, P Srinivasan… - Vaccine, 2015 - Elsevier
Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …
highly effective vaccine against infection, disease and transmission remains a key priority. It …
The path of malaria vaccine development: challenges and perspectives
C Arama, M Troye‐Blomberg - Journal of internal medicine, 2014 - Wiley Online Library
Malaria is a life‐threatening disease caused by parasites of the P lasmodium genus. In
many parts of the world, the parasites have developed resistance to a number of antimalarial …
many parts of the world, the parasites have developed resistance to a number of antimalarial …
Controlled human malaria infection of healthy adults with lifelong malaria exposure to assess safety, immunogenicity, and efficacy of the asexual blood stage malaria …
JC Dejon-Agobe, U Ateba-Ngoa… - Clinical Infectious …, 2019 - academic.oup.com
Background GMZ2 is a recombinant malaria vaccine inducing immune responses against
Plasmodium falciparum (Pf) merozoite surface protein-3 and glutamate-rich protein. We …
Plasmodium falciparum (Pf) merozoite surface protein-3 and glutamate-rich protein. We …