Homeodomain proteins: an update
TR Bürglin, M Affolter - Chromosoma, 2016 - Springer
Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …
[HTML][HTML] Congenital aniridia beyond black eyes: from phenotype and novel genetic mechanisms to innovative therapeutic approaches
Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …
been shown to be associated with other developmental ocular abnormalities and systemic …
RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants
Y Kagaya, K Ohmiya, T Hattori - Nucleic acids research, 1999 - academic.oup.com
We have cloned and characterized two novel DNA binding proteins designated RAV1 and
RAV2 from Arabidopsis thaliana. RAV1 and RAV2 contain two distinct amino acid sequence …
RAV2 from Arabidopsis thaliana. RAV1 and RAV2 contain two distinct amino acid sequence …
Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator
N Osumi, H Shinohara, K Numayama-Tsuruta… - Stem …, 2008 - academic.oup.com
Pax6 is a highly conserved transcription factor among vertebrates and is important in various
developmental processes in the central nervous system (CNS), including patterning of the …
developmental processes in the central nervous system (CNS), including patterning of the …
Pax6: a multi-level regulator of ocular development
O Shaham, Y Menuchin, C Farhy… - Progress in retinal and …, 2012 - Elsevier
Eye development has been a paradigm for the study of organogenesis, from the
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …
PAX-6 IN DEVELOPMENT AND EVOLUTION
P Callaerts, G Halder, WJ Gehring - Annual review of …, 1997 - annualreviews.org
▪ Abstract Pax-6 is a member of the Pax gene class and encodes a protein containing a
paired domain and a homeodomain. The molecular characterization of Pax-6 genes from …
paired domain and a homeodomain. The molecular characterization of Pax-6 genes from …
Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor
Understanding brain development remains a major challenge at the heart of understanding
what makes us human. The neocortex, in evolutionary terms the newest part of the cerebral …
what makes us human. The neocortex, in evolutionary terms the newest part of the cerebral …
PAX genes: roles in development, pathophysiology, and cancer
D Lang, SK Powell, RS Plummer, KP Young… - Biochemical …, 2007 - Elsevier
PAX proteins function as transcription factors and play an essential role in organogenesis
during embryonic development in regulating cell proliferation and self-renewal, resistance to …
during embryonic development in regulating cell proliferation and self-renewal, resistance to …
Pax6; a pleiotropic player in development
TI Simpson, DJ Price - Bioessays, 2002 - Wiley Online Library
Pax6 is a transcription factor essential for the development of tissues including the eyes,
central nervous system and endocrine glands of vertebrates and invertebrates. It regulates …
central nervous system and endocrine glands of vertebrates and invertebrates. It regulates …
PAX6: 25th anniversary and more to learn
A Cvekl, P Callaerts - Experimental eye research, 2017 - Elsevier
The DNA-binding transcription factor PAX6 was cloned 25 years ago by multiple teams
pursuing identification of human and mouse eye disease causing genes, cloning vertebrate …
pursuing identification of human and mouse eye disease causing genes, cloning vertebrate …