Salivary gland neoplasms are a morphologically heterogenous group of lesions that are
often diagnostically challenging. In recent years, considerable progress in salivary gland …

Adenoid cystic carcinoma (ACC) is a rare malignant tumor derived mainly from the salivary
glands, representing approximately 1% of all head and neck carcinomas and 10% of all …

Triple-negative breast cancer is viewed clinically as an aggressive subgroup of breast
cancer. In fact, most triple-negative breast cancers are poor-prognosis tumors with a …

Triple-negative breast cancers (TNBCs), defined by lack of expression of estrogen receptor,
progesterone receptor and HER2, account for 12–17% of breast cancers and are clinically …

Histologic grade is a significant predictor of outcome in salivary gland carcinomas. However,
the sheer variety of tumor type and the rarity of these tumors pose challenges to devising …

Salivary gland cancers are rare with an annual incidence of approximately 3.0 cases per
100,000 in the United States accounting for less than 3% of all head and neck cancers. They …

Dedifferentiation is a well recognized, if sometimes controversial, form of tumor progression
in certain types of soft tissue and bone sarcoma, and confers a worse prognosis when …

High-grade transformation (HGT) or dedifferentiation has been described in a variety of
salivary gland carcinomas, including acinic cell carcinoma, secretory carcinoma, adenoid …

Context Immunohistochemistry is a useful tool for diagnosing salivary gland and head and
neck tumors. Objective To review immunohistochemical markers, which can aid in the …

Adenoid cystic carcinoma is a malignant tumor with a deceptively benign histologic
appearance characterized by indolent, locally invasive growth with high propensity for local …