The germinal centre B cell response to SARS-CoV-2
BJ Laidlaw, AH Ellebedy - Nature Reviews Immunology, 2022 - nature.com
The germinal centre (GC) response is critical for the generation of affinity-matured plasma
cells and memory B cells capable of mediating long-term protective immunity …
cells and memory B cells capable of mediating long-term protective immunity …
Remembrance of things past: long-term B cell memory after infection and vaccination
AKE Palm, C Henry - Frontiers in immunology, 2019 - frontiersin.org
The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …
memory. The immune system can remember previously encountered pathogens, and …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota
Durable antibody immunity depends on long-lived plasma cells (LLPCs) that primarily reside
in the bone marrow (BM). However, due to LLPC rarity, it has not been possible to define …
in the bone marrow (BM). However, due to LLPC rarity, it has not been possible to define …
Niches for hematopoietic stem cells and their progeny
Q Wei, PS Frenette - Immunity, 2018 - cell.com
Steady-state hematopoietic stem cells'(HSCs) self-renewal and differentiation toward their
mature progeny in the adult bone marrow is tightly regulated by cues from the …
mature progeny in the adult bone marrow is tightly regulated by cues from the …
The role of tumor microenvironment in multiple myeloma development and progression
A Garcia-Ortiz, Y Rodríguez-García, J Encinas… - Cancers, 2021 - mdpi.com
Simple Summary Multiple Myeloma (MM) is a hematologic malignancy caused by aberrant
plasma cell proliferation in the bone marrow (BM) and constitutes the second most common …
plasma cell proliferation in the bone marrow (BM) and constitutes the second most common …
[HTML][HTML] Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
Resident memory B (BRM) cells develop and persist in the lungs of influenza-infected mice
and humans; however, their contribution to recall responses has not been defined. Here, we …
and humans; however, their contribution to recall responses has not been defined. Here, we …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …
performing flow cytometry experiments and includes comprehensive sections describing …
The maintenance of memory plasma cells
L Khodadadi, Q Cheng, A Radbruch… - Frontiers in …, 2019 - frontiersin.org
It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression
The gut microbiota has been causally linked to cancer, yet how intestinal microbes influence
progression of extramucosal tumors is poorly understood. Here we provide evidence …
progression of extramucosal tumors is poorly understood. Here we provide evidence …